Analytical Data
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Gene name
ENPP7
- Application
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Alternative Names
ENPP7; UNQ3077/PRO9912; Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; E-NPP 7; NPP-7; Alkaline sphingomyelin phosphodiesterase; Intestinal alkaline sphingomyelinase; Alk-SMase
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6UWV6
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Expression Region
1-458aa
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AA Sequence
MRGPAVLLTVALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALPPDGRPTLLPKGRSALPPSSRPLLVMGLLGTVILLSEVA
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Molecular Weight
77.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ENPP7 (ectonucleotide pyrophosphatase/phosphodiesterase 7) is an enzyme implicated in various physiological processes, including nucleotide metabolism and cellular signaling. As a member of the ecto-nucleotide triphosphate diphosphohydrolase family, ENPP7 plays a crucial role in hydrolyzing nucleotide triphosphates and phosphodiester bonds. Recent studies have highlighted its potential involvement in pathological conditions, such as cancer and neurodegenerative diseases, where aberrant nucleotide signaling can influence cell proliferation, differentiation, and apoptosis. The interest in recombinant ENPP7 protein has surged due to its potential use in therapeutic applications, biomarker discovery, and elucidating its role in biological pathways. Understanding the biochemical properties of ENPP7, including its substrate specificity and regulatory mechanisms, could provide insights into developing novel strategies for modulating its activity. Furthermore, recombinant ENPP7 can serve as a valuable tool for structural and functional studies, aiding in the development of inhibitors or modulators that could target its enzymatic function. As a result, research into recombinant ENPP7 is a promising area that may yield significant advancements in both basic biology and clinical applications.
