Analytical Data
-
Gene name
ENPP6
- Application
-
Alternative Names
ENPP6; UNQ1889/PRO4334Glycerophosphocholine cholinephosphodiesterase ENPP6; GPC-Cpde; EC 3.1.4.-; EC 3.1.4.38; Choline-specific glycerophosphodiester phosphodiesterase; Ectonucleotide pyrophosphatase/phosphodiesterase family member 6; E-NPP 6; NPP-6
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q6UWR7
-
Expression Region
1-440aa
-
AA Sequence
MAVKLGTLLLALALGLAQPASARRKLLVFLLDGFRSDYISDEALESLPGFKEIVSRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEVHQMIGNYMWDPTTNKSFDIGVNKDSLMPLWWNGSEPLWVTLTKAKRKVYMYYWPGCEVEILGVRPTYCLEYKNVPTDINFANAVSDALDSFKSGRADLAAIYHERIDVEGHHYGPASPQRKDALKAVDTVLKYMTKWIQERGLQDRLNVIIFSDHGMTDIFWMDKVIELNKYISLNDLQQVKDRGPVVSLWPAPGKHSEIYNKLSTVEHMTVYEKEAIPSRFYYKKGKFVSPLTLVADEGWFITENREMLPFWMNSTGRREGWQRGWHGYDNELMDMRGIFLAFGPDFKSNFRAAPIRSVDVYNVMCNVVGITPLPNNGSWSRVMCMLKGRASTAPPVWPSHCALALILLFLLA
-
Molecular Weight
76.6 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ENPP6, or ecto-nucleotide pyrophosphatase/phosphodiesterase 6, is an enzyme that plays a crucial role in the metabolism of extracellular nucleotides and nucleotide derivatives, impacting various physiological processes. Research on ENPP6 is driven by its potential involvement in purinergic signaling, neuronal development, and the modulation of inflammatory responses. Recent studies have suggested that ENPP6 may also be linked to neurodegenerative diseases and cancer, highlighting its significance in both health and disease contexts. The production of recombinant ENPP6 protein is essential for in-depth functional analyses, structural studies, and therapeutic applications. By utilizing techniques such as recombinant DNA technology and protein expression systems, researchers aim to produce active forms of the protein for biochemical characterization and to explore its enzymatic properties. Understanding the structure-function relationships of ENPP6 may lead to insights into its mechanisms of action and its roles in various biological systems, paving the way for potential drug development or biomarker identification. Therefore, the study of ENPP6 recombinant protein not only enriches our comprehension of nucleotide metabolism but also opens new avenues for therapeutic interventions in related disorders.
