Analytical Data
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基因名
ZBTB33
- Application
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别名
Kaiso; Kaiso Protein; Kaiso transcription factor; KAISO_HUMAN; Transcriptional regulator Kaiso; ZBTB 33; Zbtb33; Zinc finger and BTB domain containing 33; Zinc finger and BTB domain-containing Protein 33; Zinc finger transcription factor Kaiso; ZNF 348; ZNF Kaiso; ZNF348
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86T24
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表达区间
1-673 aa
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氨基酸序列
MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTAQDGNTEPLPPDSGDKNLVIQKSKDEAQDNGATIMPIITESFSLSAEDYEMKKIIVTDSDDDDDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVAISDVAPSASNNSPPLTNITPTQKLPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHMPSSINLLVQNQQTPNSAILTGNKANEEEEEEIIDDDDDTISSSPDSAVSNTSLVPQADTSQNTSFDGSLIQKMQIPTLLQEPLSNSLKISDIITRNTNDPGVGSKHLMEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDEGEARLENEIPKTSGSEMANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCRSLQIRQYAYLSDRSSTIPAMKDDGIGYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY
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分子量
101 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZBTB33, a member of the ZBTB (Zinc Finger and BTB Domain Containing) family of proteins, has garnered increased attention in recent years due to its potential roles in various biological processes, including gene regulation, cell growth, and differentiation. This protein is characterized by the presence of zinc finger motifs, which facilitate DNA binding, and a BTB (Bric-a-Brac, Tramtrack, and Broad Complex) domain that is implicated in protein-protein interactions. Research has indicated that ZBTB33 may play a significant role in the regulation of immune responses and may be involved in the development of certain cancers. For instance, aberrant expression of ZBTB33 has been linked to tumorigenesis and metastasis, suggesting that it may function as a tumor suppressor or promoter, depending on the context. Moreover, recent studies have shown that ZBTB33 can modulate the expression of various target genes, influencing cellular pathways that govern cellular proliferation and apoptosis. The exploration of ZBTB33 as a recombinant protein is therefore critical for understanding its mechanistic roles and therapeutic potential. By producing ZBTB33 in a laboratory setting, researchers aim to elucidate its structure-function relationships and its interactions with other cellular components. This research may pave the way for the development of novel therapeutic strategies targeting ZBTB33 in diseases where its regulatory functions are disrupted. Overall, the study of ZBTB33 as a recombinant protein stands as a promising avenue for advancing our understanding of cellular regulation and potential interventions in cancer biology and immune disorders.
