Analytical Data
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Gene name
ZBTB33
- Application
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Alternative Names
Kaiso; Kaiso Protein; Kaiso transcription factor; KAISO_HUMAN; Transcriptional regulator Kaiso; ZBTB 33; Zbtb33; Zinc finger and BTB domain containing 33; Zinc finger and BTB domain-containing Protein 33; Zinc finger transcription factor Kaiso; ZNF 348; ZNF Kaiso; ZNF348
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86T24
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Expression Region
1-673 aa
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AA Sequence
MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTAQDGNTEPLPPDSGDKNLVIQKSKDEAQDNGATIMPIITESFSLSAEDYEMKKIIVTDSDDDDDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVAISDVAPSASNNSPPLTNITPTQKLPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHMPSSINLLVQNQQTPNSAILTGNKANEEEEEEIIDDDDDTISSSPDSAVSNTSLVPQADTSQNTSFDGSLIQKMQIPTLLQEPLSNSLKISDIITRNTNDPGVGSKHLMEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDEGEARLENEIPKTSGSEMANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCRSLQIRQYAYLSDRSSTIPAMKDDGIGYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY
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Molecular Weight
101 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZBTB33, a member of the ZBTB (Zinc Finger and BTB Domain Containing) family of proteins, has garnered increased attention in recent years due to its potential roles in various biological processes, including gene regulation, cell growth, and differentiation. This protein is characterized by the presence of zinc finger motifs, which facilitate DNA binding, and a BTB (Bric-a-Brac, Tramtrack, and Broad Complex) domain that is implicated in protein-protein interactions. Research has indicated that ZBTB33 may play a significant role in the regulation of immune responses and may be involved in the development of certain cancers. For instance, aberrant expression of ZBTB33 has been linked to tumorigenesis and metastasis, suggesting that it may function as a tumor suppressor or promoter, depending on the context. Moreover, recent studies have shown that ZBTB33 can modulate the expression of various target genes, influencing cellular pathways that govern cellular proliferation and apoptosis. The exploration of ZBTB33 as a recombinant protein is therefore critical for understanding its mechanistic roles and therapeutic potential. By producing ZBTB33 in a laboratory setting, researchers aim to elucidate its structure-function relationships and its interactions with other cellular components. This research may pave the way for the development of novel therapeutic strategies targeting ZBTB33 in diseases where its regulatory functions are disrupted. Overall, the study of ZBTB33 as a recombinant protein stands as a promising avenue for advancing our understanding of cellular regulation and potential interventions in cancer biology and immune disorders.
