Cat: PA1000-8140

Recombinant Human BSDL Protein,His

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Analytical Data

  • Gene name

    BSDL

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    BSDL;bsdl;bssl;cease;Carboxylic ester hydrolase

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    B0BM89

  • Expression Region

    1-552aa

  • AA Sequence

    MALWATLTLAMACLVVAHAKTLGVVHTEGGFVEGTNKKIGVVFPDYIDIFKGIPFAAPPKPFEKAEKHPGWSGTLQAKDYKPRCLQATITQDNVFGSLDCLYLNVWVPQTRSQVSTNLPVMVWIFGGGFLLGSGQGANFLSNYLYDGEEVAMRGKVIVVTFNYRVGPLGFLSTGDSNAPGNYGLWDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLTPYNVGLIKRAISQSGVGLCPWAIQRDPLTWAKSLASKLGCPVNNTKELADCLRNTDPGALTIAYQLQLFNLEYPLVHYLAYSPVIDGDFIPDEPRNLFSNAAGVDYIAGVNNMDGHLFAGVDLPAINQPLHKISTEQVQKVVRGLTLAKGVPALDIAYDLYTAGWGTNPSQEDMKRTVVEVETDYIFLVATQEALALHYQNAKGAKTYSYMFSHPSRMPVYPSWMGADHAEDLQFMFGKPFSTPLAYRPRDRDVAQYMIAYWTNFAATGDPSKGESSIPTPWLAYSTENGQYLEINHKINYQSMKQSLRSPYVRFWAQTFINLPNA

  • Molecular Weight

    60.7 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

The study of BSDL (Bile Salt-Degrading Lactobacillus) recombinant proteins has gained significant attention in recent years due to the increasing interest in gut health and microbiome modulation. BSDL proteins are produced by specific strains of Lactobacillus, which play a crucial role in the breakdown of bile salts in the gastrointestinal tract. This process not only aids in the digestion and absorption of dietary fats but also has implications for cholesterol metabolism and overall cholesterol homeostasis. With rising rates of metabolic disorders and cardiovascular diseases linked to dysbiosis in gut microbiota, the therapeutic potential of BSDL recombinant proteins has become a focal point of research. These proteins are being explored for their ability to restore healthy gut microbiota, enhance digestion, and provide health benefits, such as lowering cholesterol levels and improving gut barrier function. Furthermore, advances in genetic engineering and recombinant DNA technology have allowed researchers to produce and study BSDL proteins in greater detail, paving the way for potential applications in functional foods, probiotics, and biotherapeutics. The continuous evolution of our understanding of gut microbiota's role in human health underscores the need for ongoing research into BSDL recombinant proteins, which may offer innovative strategies for promoting digestive health and preventing chronic diseases.

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