Analytical Data
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Gene name
TAS2R40
- Application
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Alternative Names
TAS2R40; GPR60; Taste receptor type 2 member 40; T2R40; G-protein coupled receptor 60; Taste receptor type 2 member 58; T2R58
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P59535
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Expression Region
298-323 aa
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AA Sequence
LGNPGLRRAWKRFQHQVPLYLKGQTL
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Molecular Weight
36.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TAS2R40 is a member of the bitter taste receptor family, which plays a significant role in the detection of bitter compounds across various organisms. Research on TAS2R40 has gained traction due to its potential implications in food preferences, nutrition, and even aversive behavior towards certain toxins, providing insights into dietary choices and their evolutionary significance. The receptor is activated by specific bitter compounds and is involved in the signaling pathways that mediate the gustatory response. Understanding the structural and functional properties of TAS2R40 through recombinant protein techniques can enhance our knowledge of how humans perceive bitterness and how this perception influences eating habits and health. Moreover, this knowledge could be leveraged in developing strategies to manipulate taste perception, which is particularly relevant in industries such as food and pharmaceuticals, where modulating taste can improve consumer acceptance of certain products. Biochemical studies focusing on the reconstitution of TAS2R40 in various systems help delineate its pharmacological profile and interactions with different ligands, contributing to our understanding of its role in taste perception and its potential applications in improving dietary choices and health outcomes. As such, TAS2R40 serves as a vital target for research aimed at elucidating the complexities of taste signaling and its broader implications for human behavior and health.
