Analytical Data
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Gene name
WDR49
- Application
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Alternative Names
WDR49WD repeat-containing Protein 49
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IV35
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Expression Region
1-697 aa
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AA Sequence
MAWREKSKKR LNMTSFNIAQ GIHAFDYHSR LNLIATAGIN NKVCLWNPYV VSKPVGVLWG HSASVIAVQF FVERKQLFSF SKDKVLRLWD IQHQLSIQRI ACSFPKSQDF RCLFHFDEAH GRLFISFNNQ LALLAMKSEA SKRVKSHEKA VTCVLYNSIL KQVISSDTGS TVSFWMIDTG QKIKQFTGCH GNAEISTMAL DANETRLLTG STDGTVKIWD FNGYCHHTLN VGQDGAVDIS QILILKKKIL VTGWERAITV FRPQNFNQFF IQPEEWKGGI QHHDDILCAA FLPPQTLVTG SYDGEIVLWN NSTENAHHVL HPDYQRLLKS KLDTKPQKLL SAGRSQPSHP MADHSTTGVR NFEIDTEGKN AVMRLCFLKA RKNTAVTGGA NLVSCGGSGY VRFWDIYKKQ LLAEFLAHSG VGSIIMSTDK MNRYLTTGDL DGWLKIWNIE EYCLNSSKNK ITKAPTLIRS FQPHEDRISS LEMCEPGGQL LIISSSADCS ICVTGVCNAP VWIFGQAKHW HIENCLFLPK RDTNLVESEI QKEISLFSKE ESCLDPTEHS LLNKKNKDDS TYNVRPSEDI NLDIKYKERS TCMKETQKPY YGEVIKKSFS TFRSLNIGAL EELPEVNKPA FLLDPEKYFR KEPEEERPQI LEAPSLFKTL KAVFDEKNLF PKEILHHERK AKQLCQEKSC EVKKNKK
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Molecular Weight
119.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
WDR49, or WD repeat domain 49, is a protein that belongs to the WD repeat protein family, which is characterized by the presence of multiple WD repeats involved in protein-protein interactions and cellular signaling pathways. Recent studies have highlighted WDR49's potential role in various biological processes such as cell proliferation, differentiation, and apoptosis. The exploration of WDR49 as a recombinant protein is significant for understanding its functional mechanisms and potential implications in human health and disease. Research has suggested that WDR49 is involved in the regulation of several key cellular functions, including cytoskeletal organization and signal transduction pathways, thereby influencing cellular responses to environmental cues. Additionally, WDR49 has been implicated in certain pathological conditions, including cancer, where dysregulation of its function can lead to uncontrolled cell growth. The generation of WDR49 recombinant proteins allows for the detailed study of its structure, biological activity, and interactions with other cellular proteins, providing insights into its role in normal physiology and disease states. Such investigations can enhance our understanding of the molecular underpinnings of WDR49-related disorders and may pave the way for the development of targeted therapeutic strategies. Overall, research on WDR49 recombinant proteins is crucial for unraveling the complexities of its functions and contributions to cellular dynamics.
