Analytical Data
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Gene name
SUDS3
- Application
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Alternative Names
2400003N08Rik; 2410008L21Rik; 45 kDa Sin3 associated polypeptide; 45 kDa Sin3-associated polypeptide; AU067672; FLJ00052; MGC104711; mSds3; RGD1305986; SAP45; SDS3; SDS3. yeast. homolog of; SDS3_HUMAN; Sin3 histone deacetylase corepressor complex component SDS3; Sin3A associated protein 45kDa; Suds3; Suppressor of defective silencing 3; Suppressor of defective silencing 3 homolog (S cerevisiae); Suppressor of defective silencing 3 homolog (SDS3 S cerevisiae); Suppressor of defective silencing 3 protein homolog
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H7L9
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Expression Region
2-328 aa
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AA Sequence
SAAGLLAPA PAQAGAPPAP EYYPEEDEEL ESAEDDERSC RGRESDEDTE DASETDLAKH DEEDYVEMKE QMYQDKLASL KRQLQQLQEG TLQEYQKRMK KLDQQYKERI RNAELFLQLE TEQVERNYIK EKKAAVKEFE DKKVELKENL IAELEEKKKM IENEKLTMEL TGDSMEVKPI MTRKLRRRPN DPVPIPDKRR KPAPAQLNYL LTDEQIMEDL RTLNKLKSPK RPASPSSPEH LPATPAESPA QRFEARIEDG KLYYDKRWYH KSQAIYLESK DNQKLSCVIS SVGANEIWVR KTSDSTKMRI YLGQLQRGLF VIRRRSAA
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Molecular Weight
38.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The SUDS3 protein, also known as Su(var)3-9, Enhancer of zeste, and Trithorax domain-containing protein 3, plays a critical role in chromatin remodeling and gene regulation. Research surrounding SUDS3 has gained momentum due to its involvement in various biological processes and its implications in several diseases, including cancer and developmental disorders. It operates as a component of the multi-protein complexes that modify histones and remodel chromatin, thereby influencing transcriptional regulation of target genes. SUDS3 has been linked to the regulation of stem cell pluripotency, differentiation, and cellular response to environmental cues, making it vital for maintaining normal cellular functions. Furthermore, aberrations in SUDS3 expression or function can lead to epigenetic alterations that contribute to oncogenesis and disease progression. Thus, understanding the structural and functional characteristics of SUDS3, including its interaction with other proteins and DNA, is paramount for developing targeted therapeutic strategies, particularly in cancer research and regenerative medicine. Recent advancements in recombinant protein production have facilitated detailed studies on SUDS3, enhancing our knowledge of its mechanism of action and potential roles in the epigenetic landscape. As a result, SUDS3 continues to be a focal point of scientific inquiry, promising new insights into the intricate regulation of gene expression and the potential for novel biomarker and therapeutic development.
