Analytical Data
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Gene name
ARRDC4
- Application
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Alternative Names
ARRD4_HUMAN; ARRDC 4; Arrdc4; Arrestin domain containing Protein 4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NCT1
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Expression Region
1-418aa
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AA Sequence
MGGEAGCAAA VGAEGRVKSL GLVFEDERKG CYSSGETVAG HVLLEASEPV ALRALRLEAQ GRATAAWGPS TCPRASASTA ALAVFSEVEY LNVRLSLREP PAGEGIILLQ PGKHEFPFRF QLPSEPLVTS FTGKYGSIQY CVRAVLERPK VPDQSVKREL QVVSHVDVNT PALLTPVLKT QEKMVGCWFF TSGPVSLSAK IERKGYCNGE AIPIYAEIEN CSSRLIVPKA AIFQTQTYLA SGKTKTIRHM VANVRGNHIA SGSTDTWNGK TLKIPPVTPS ILDCCIIRVD YSLAVYIHIP GAKKLMLELP LVIGTIPYNG FGSRNSSIAS QFSMDMSWLT LTLPEQPEAP PNYADVVSEE EFSRHIPPYP QPPNCEGEVC CPVFACIQEF RFQPPPLYSE VDPHPSDVEE SQPVSFIL
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Molecular Weight
45.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ARRDC4, a member of the arrestin-related domain-containing protein family, has garnered significant attention in recent years due to its potential roles in various cellular processes and its implications in diseases. Initially identified for its involvement in the regulation of G protein-coupled receptor signaling, ARRDC4 has since been linked to diverse functions, including protein sorting, endocytosis, and modulation of cell signaling pathways. Research has shown that ARRDC4 can influence the trafficking of membrane proteins, thereby affecting cellular homeostasis and communication. Its dysregulation has been associated with various pathophysiological conditions, including cancers and metabolic disorders, making it a promising candidate for therapeutic intervention. Understanding the structure and function of ARRDC4 recombinant proteins could provide insights into their mechanisms of action and potential clinical applications. The development of recombinant ARRDC4 allows researchers to delve deeper into its biochemical properties and interactions, paving the way for novel strategies in targeting diseases related to its dysfunction. Overall, the study of ARRDC4 and its recombinant proteins holds great promise for uncovering new biological insights and therapeutic avenues in the field of cell biology and medicine.
