Analytical Data
-
Gene name
ARRDC3
- Application
-
Alternative Names
ARRDC3; KIAA1376; Arrestin domain-containing Protein 3; TBP-2-like inducible membrane Protein; TLIMP
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q96B67
-
Expression Region
1-414aa
-
AA Sequence
MVLGKVKSLT ISFDCLNDSN VPVYSSGDTV SGRVNLEVTG EIRVKSLKIH ARGHAKVRWT ESRNAGSNTA YTQNYTEEVE YFNHKDILIG HERDDDNSEE GFHTIHSGRH EYAFSFELPQ TPLATSFEGR HGSVRYWVKA ELHRPWLLPV KLKKEFTVFE HIDINTPSLL SPQAGTKEKT LCCWFCTSGP ISLSAKIERK GYTPGESIQI FAEIENCSSR MVVPKAAIYQ TQAFYAKGKM KEVKQLVANL RGESLSSGKT ETWNGKLLKI PPVSPSILDC SIIRVEYSLM VYVDIPGAMD LFLNLPLVIG TIPLHPFGSR TSSVSSQCSM NMNWLSLSLP ERPEAPPSYA EVVTEEQRRN NLAPVSACDD FERALQGPLF AYIQEFRFLP PPLYSEIDPN PDQSADDRPS CPSR
-
Molecular Weight
46 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ARRDC3 (Arrestin Domain Containing 3) is a member of the arrestin family of proteins, which play crucial roles in regulating G protein-coupled receptor (GPCR) signaling and endocytic processes. Research into ARRDC3 has gained significant attention due to its involvement in various cellular functions, including receptor desensitization, internalization, and trafficking. ARRDC3 has been implicated in the modulation of numerous signaling pathways and is thought to participate in the regulation of cell surface receptor levels, impacting cellular responsiveness to external stimuli. Additionally, studies suggest that ARRDC3 may play a role in cancer progression and metastasis, making it a potential target for therapeutic interventions. The production of recombinant ARRDC3 protein in vitro is essential for understanding its structure-function relationships, interaction with other cellular proteins, and its role in disease mechanisms. This knowledge could lead to the identification of novel drug targets and the development of innovative treatment strategies. Overall, the study of ARRDC3 recombinant protein is vital for elucidating the complex molecular interactions that govern cell signaling and for advancing our understanding of its contributions to health and disease.
