Analytical Data
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基因名
SOX4
- Application
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别名
SOX4；Transcription factor SOX-4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q06945
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表达区间
1-474aa
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氨基酸序列
MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLGSFSSSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWLESSISNLVFTY
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分子量
47 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SOX4 (SRY-related HMG-box 4) is a transcription factor belonging to the SOX family, which plays a crucial role in embryonic development and cellular differentiation. It is implicated in various biological processes, including cell fate determination, stem cell maintenance, and tumorigenesis. Abnormal expression of SOX4 has been linked to several cancers, making it a significant target for cancer research. The study of recombinant SOX4 protein is essential for understanding its structure-function relationship and regulatory mechanisms. Researchers aim to produce and characterize this protein to investigate its role in signaling pathways, gene regulation, and developmental processes. The ability to express the SOX4 protein in a recombinant form allows for detailed biochemical analyses, including binding affinities and interactions with other proteins or DNA. Furthermore, understanding the molecular basis of SOX4 function could lead to potential therapeutic applications, such as targeting its pathways in cancer treatment. Given the increasing emphasis on precision medicine and targeted therapies, elucidating the precise roles of transcription factors like SOX4 could provide valuable insights into the development of novel strategies for cancer intervention and other diseases associated with its dysregulation.
