Analytical Data
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Gene name
ARMCX2
- Application
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Alternative Names
ALEX 2; ALEX2; ARM Protein lost in epithelial cancers on chromosome X 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7L311
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Expression Region
1-632aa
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AA Sequence
MSRVRDAGCVAAGIVIGAGAWYCVYKYTRGRDQTKKRMAKPKNRAVAGTGARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAGVGPKAESVVGAAMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEAPVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAVPKGGGKGVTRSRNGGKGKGKKSKVEVDELGMGFRPGDGAAAAAAASANGGQAFLAEVPDSEEGESGWTDTESDSDSEPETQRRGRGRRPVAMQKRPFPYEIDEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKALMAMNNLSENYENQGRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDMLKKLLSTQVPASFSSLYNSYVESEILINALTLFEIIYDNLRAEVFNYREFNKGSLFYLCTTSGVCVKKIRALANHHDLLVKVKVIKLVNKF
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Molecular Weight
65 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ARMCX2 (Armadillo Repeat Containing X-Linked 2) is a gene that encodes a protein involved in various cellular processes, including signal transduction, cell adhesion, and cytoskeletal organization. Research on ARMCX2 has gained attention due to its potential role in neurodevelopmental disorders and its association with X-linked intellectual disabilities. The protein features multiple armadillo repeats, which are structural motifs commonly found in proteins that mediate protein-protein interactions. Understanding how ARMCX2 operates at the molecular level may reveal its contribution to the pathogenesis of certain diseases, particularly those affecting cognitive function and neural development. Recent studies suggest that mutations in the ARMCX2 gene can disrupt normal cellular functions, leading to a spectrum of neurological and behavioral anomalies. Therefore, investigating the function of the ARMCX2 recombinant protein can provide insights into its biological significance and therapeutic potential. The recombinant version of this protein allows researchers to study its interactions, binding capabilities, and functional mechanisms in a controlled environment, thus paving the way for possible interventions to mitigate the impact of ARMCX2-related disorders. Such research is crucial not only for understanding basic biological processes but also for developing targeted therapies for individuals affected by abnormalities associated with ARMCX2.
