Analytical Data
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Gene name
TINAG
- Application
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Alternative Names
TINAG；Tubulointerstitial nephritis antigen
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UJW2
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Expression Region
1-476aa
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AA Sequence
MWTGYKILIF SYLTTEIWME KQYLSQREVD LEAYFTRNHT VLQGTRFKRA IFQGQYCRNF GCCEDRDDGC VTEFYAANAL CYCDKFCDRE NSDCCPDYKS FCREEKEWPP HTQPWYPEGC FKDGQHYEEG SVIKENCNSC TCSGQQWKCS QHVCLVRSEL IEQVNKGDYG WTAQNYSQFW GMTLEDGFKF RLGTLPPSPM LLSMNEMTAS LPATTDLPEF FVASYKWPGW THGPLDQKNC AASWAFSTAS VAADRIAIQS KGRYTANLSP QNLISCCAKN RHGCNSGSID RAWWYLRKRG LVSHACYPLF KDQNATNNGC AMASRSDGRG KRHATKPCPN NVEKSNRIYQ CSPPYRVSSN ETEIMKEIMQ NGPVQAIMQV REDFFHYKTG IYRHVTSTNK ESEKYRKLQT HAVKLTGWGT LRGAQGQKEK FWIAANSWGK SWGENGYFRI LRGVNESDIE KLIIAAWGQL TSSDEP
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Molecular Weight
54.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TINAG (Tubulointerstitial Nephritis Antigen) is a protein that has garnered significant interest in the field of renal research, particularly due to its role in renal pathologies and potential implications in kidney diseases. Initially identified in the context of tubulointerstitial nephritis, TINAG is thought to be involved in various cellular processes, including inflammation, apoptosis, and extracellular matrix interactions. The importance of TINAG is underscored by its expression patterns in renal tissues and its association with kidney injury and repair mechanisms. Studies suggest that the dysregulation of TINAG may contribute to the progression of chronic kidney disease and other renal disorders. Given its pivotal role in kidney health, researchers are increasingly focused on elucidating the biochemical properties of TINAG and its mechanisms of action. The development of recombinant TINAG proteins has opened avenues for experimental studies, allowing for the exploration of its functional roles in vitro and in vivo. Investigating TINAG's structure-function relationships may not only yield insights into kidney disease pathology but also identify potential therapeutic targets. Overall, the ongoing research on TINAG promises to enhance our understanding of kidney function and disease, with the potential to improve diagnostic and therapeutic strategies for renal disorders.
