Cat: PA2000-9978

Recombinant Human OR5B21 Protein,His

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Analytical Data

  • Gene name

    OR5B21

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    OR5B21; Olfactory receptor 5B21

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    A6NL26

  • Expression Region

    1-309 aa

  • AA Sequence

    MENSTEVTEFILLGLTDDPNLQIPLLLAFLFIYLITLLGNGGMMVIIHSDSHLHTPMYFF LSNLSLVDLGYSSAVAPKTVAALRSGDKAISYDGCAAQFFFFVGFATVECYLLASMAYDR HAAVCRPLHYTTTMTAGVCALLATGSYVSGFLNASIHAAGTFRLSFCGSNEINHFFCDIP PLLALSCSDTRISKLVVFVAGFNVFFTLLVILISYFFICITIQRMHSAEGQKKVFSTCAS HLTALSIFYGTIIFMYLQPNSSQSVDTDKIASVFYTVVIPMLNPLIYSLRNKEVKSALWK ILNKLYPQY

  • Molecular Weight

    34.1 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

The OR5B21 gene encodes a member of the olfactory receptor (OR) family, which plays a crucial role in the detection of odorants, contributing to the sense of smell in mammals. These G-protein coupled receptors are primarily located in the olfactory epithelium and are responsible for initiating the signaling cascade that allows for the perception of various odors. The unique structure and function of OR5B21, as with other olfactory receptors, make it a subject of interest for researchers aiming to understand olfactory mechanisms, scent recognition, and receptor activation. Additionally, studies on OR5B21 have implications for neurobiology, as the olfactory system is closely linked to memory and emotion. However, the functional characterization of OR5B21 has been limited due to challenges in expressing and purifying the protein in recombinant systems. Recent advancements in protein engineering and expression technologies have opened new avenues for the study of OR5B21, enabling researchers to explore its ligand-binding properties, downstream signaling pathways, and potential involvement in olfactory-related disorders. By elucidating the functional characteristics of OR5B21, researchers hope to contribute valuable insights into the broader field of olfactory receptor biology and its relevance to human health.

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