Analytical Data
-
Gene name
CSAD
- Application
-
Alternative Names
CSAD；CSD；Cysteine sulfinic acid decarboxylase
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9Y600
-
Expression Region
1-493aa
-
AA Sequence
MADSEALPSL AGDPVAVEAL LRAVFGVVVD EAIQKGTSVS QKVCEWKEPE ELKQLLDLEL RSQGESQKQI LERCRAVIRY SVKTGHPRFF NQLFSGLDPH ALAGRIITES LNTSQYTYEI APVFVLMEEE VLRKLRALVG WSSGDGIFCP GGSISNMYAV NLARYQRYPD CKQRGLRTLP PLALFTSKEC HYSIQKGAAF LGLGTDSVRV VKADERGKMV PEDLERQIGM AEAEGAVPFL VSATSGTTVL GAFDPLEAIA DVCQRHGLWL HVDAAWGGSV LLSQTHRHLL DGIQRADSVA WNPHKLLAAG LQCSALLLQD TSNLLKRCHG SQASYLFQQD KFYDVALDTG DKVVQCGRRV DCLKLWLMWK AQGDQGLERR IDQAFVLARY LVEEMKKREG FELVMEPEFV NVCFWFVPPS LRGKQESPDY HERLSKVAPV LKERMVKEGS MMIGYQPHGT RGNFFRVVVA NSALTCADMD FLLNELERLG QDL
-
Molecular Weight
55 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CSAD (Cysteine Sulfinic Acid Decarboxylase) is an enzyme involved in the biosynthesis of the neurotransmitter taurine, which plays critical roles in various physiological processes, including osmoregulation, calcium homeostasis, and modulation of neurotransmitter release. The study of CSAD has gained prominence due to its potential implications in neurological disorders, as taurine deficiency has been linked to conditions such as epilepsy, neurodegeneration, and developmental disorders. Researchers have focused on the structural and functional characterization of CSAD to understand its catalytic mechanisms and regulatory pathways. Recent advances in protein engineering and molecular biology techniques have facilitated the production of recombinant CSAD, allowing for detailed studies of its kinetics, substrate specificity, and interaction with other biomolecules. By elucidating the role of CSAD in taurine metabolism and its broader biological functions, scientists aim to identify potential therapeutic targets for treating related disorders. The exploration of CSAD's structural features and its modulation could pave the way for novel approaches in drug design and development, highlighting the significance of this enzyme in both basic research and clinical applications.
