Analytical Data
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Gene name
SUOX
- Application
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Alternative Names
SUOX；Sulfite oxidase. mitochondrial
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P51687
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Expression Region
80-545aa
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AA Sequence
MGSSHHHHHHSSGLVPRGSHMGSESTHIYTKEEVSSHTSPETGIWVTLGS EVFDVTEFVDLHPGGPSKLMLAAGGPLEPFWALYAVHNQSHVRELLAQYK IGELNPEDKVAPTVETSDPYADDPVRHPALKVNSQRPFNAEPPPELLTEN YITPNPIFFTRNHLPVPNLDPDTYRLHVVGAPGGQSLSLSLDDLHNFPRY EITVTLQCAGNRRSEMTQVKEVKGLEWRTGAISTARWAGARLCDVLAQAG HQLCETEAHVCFEGLDSDPTGTAYGASIPLARAMDPEAEVLLAYEMNGQP LPRDHGFPVRVVVPGVVGARHVKWLGRVSVQPEESYSHWQRRDYKGFSPS VDWETVDFDSAPSIQELPVQSAITEPRDGETVESGEVTIKGYAWSGGGRA VIRVDVSLDGGLTWQVAKLDGEEQRPRKAWAWRLWQLKAPVPAGQKELNI VCKAVDDGYNVQPDTVAPIWNLRGVLSNAW HRVHVYVSP
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Molecular Weight
54 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SUOX (sulfite oxidase) is a crucial enzyme in the human body that plays a significant role in the metabolism of sulfur-containing amino acids, specifically in the conversion of sulfite to sulfate, a process vital for the detoxification of sulfite. Deficiencies in SUOX can lead to sulfite accumulation, resulting in severe neurological disorders and other health issues. Research into SUOX has gained momentum due to the potential therapeutic implications for treating sulfite-related diseases, including sulfite oxidase deficiency, characterized by developmental delays and other neurological symptoms. Recombinant SUOX protein has been explored as a promising avenue for enzyme replacement therapy or as a tool for investigating the biochemical pathways involving sulfur metabolism. The production and characterization of recombinant SUOX allow researchers to study its kinetic properties, structure-function relationships, and interactions with various substrates and inhibitors. Enhanced understanding of SUOX functionality could pave the way for novel treatment strategies and contribute to our knowledge of related metabolic disorders, emphasizing the relevance of SUOX research in the fields of biochemistry and medicine. Furthermore, advancements in gene editing technologies and synthetic biology may further facilitate the development of SUOX-based therapies, potentially offering new hope for individuals affected by sulfite intolerances and related conditions.
