Analytical Data
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Gene name
RGS16
- Application
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Alternative Names
RGS16;RGSR;Regulator of G-Protein signaling 16
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15492
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Expression Region
1-202aa
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AA Sequence
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
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Molecular Weight
30.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RGS16 (Regulator of G protein Signaling 16) is a member of the RGS protein family, known for its role in modulating G protein-coupled receptor (GPCR) signaling pathways. Research has highlighted its significance in various physiological processes, including immune response, neural signaling, and cellular proliferation. Dysregulation of RGS16 has been implicated in several diseases, such as cancer and neurological disorders, making it a potential therapeutic target. The study of recombinant RGS16 protein not only aids in understanding its structural and functional properties but also facilitates the exploration of its interactions with G proteins and receptors. By generating and characterizing RGS16 recombinant proteins, researchers can investigate the mechanisms through which RGS16 influences signaling pathways and contributes to cellular responses. Furthermore, recombinant RGS16 can be utilized in high-throughput screening assays to identify small molecules that modulate its activity, paving the way for drug development aimed at restoring normal signaling processes in pathological conditions. Overall, the comprehensive study of RGS16, including the analysis of its recombinant form, holds promise for elucidating its role in health and disease, leading toward novel therapeutic strategies.
