Analytical Data
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基因名
BMP2
- Application
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别名
BMP2;BMP2A;Bone morphogenetic Protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P12643
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表达区间
283-396aa
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氨基酸序列
MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
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分子量
13 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Bone morphogenetic protein-2 (BMP2) is a crucial member of the transforming growth factor-beta (TGF-β) superfamily, known for its pivotal role in osteogenesis and bone regeneration. Initially identified for its ability to induce bone formation, BMP2 has garnered significant attention in the fields of tissue engineering and regenerative medicine. Researchers have explored the recombinant expression of BMP2 to develop therapeutic applications, particularly for bone defects and fractures that fail to heal properly. The recombinant protein is typically produced in various expression systems, allowing for the generation of bioactive BMP2 at scale. Studies have demonstrated that BMP2 can promote the proliferation and differentiation of osteoblasts, the cells responsible for bone formation, thereby enhancing the healing process in bone-related injuries. Furthermore, BMP2's signaling pathway has been implicated in various physiological processes, including embryonic development and tissue homeostasis. Given its multifaceted roles, understanding BMP2’s mechanisms of action and improving its delivery and effectiveness remain critical focal points in the ongoing research. Advances in biomaterial technology, gene therapy, and controlled-release systems have the potential to optimize BMP2 applications, making it a promising candidate for clinical therapies aimed at addressing bone-related conditions. Overall, the study of BMP2 recombinant protein continues to be a vibrant area of research with significant implications for enhancing bone repair strategies in the medical field.












