Analytical Data
-
基因名
BLOC1S2
- Application
-
别名
BLOC1S2；BLOS2；CEAP；Biogenesis of lysosome-related organelles complex 1 subunit 2
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q6QNY1-2
-
表达区间
2-99aa
-
氨基酸序列
FSKMATYLTGELTATSEDYKLLENMNKLTSLKYLEMKDIAINISRNLKDL NQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLEAKYKKLEKR
-
分子量
11 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BLOC1S2 (Biogenesis of Lysosomal Organelles Complex 1 Subunit 2) is a protein involved in the biogenesis of lysosomes and the trafficking of lysosomal enzymes. It is part of a multi-protein complex that plays a crucial role in maintaining cellular homeostasis and is implicated in the proper functioning of the endosomal-lysosomal system. Research into BLOC1S2 has gained significance due to its association with various genetic disorders, particularly those affecting lysosomal function, such as Hermansky-Pudlak syndrome. Mutations in the BLOC1S2 gene have been linked to impaired pigment cell function and immune system responses, highlighting its importance in cellular integrity and health. Furthermore, understanding the molecular mechanisms underlying BLOC1S2 function could provide insights into therapeutic strategies for lysosomal storage diseases and other disorders related to lysosomal dysfunction. The ongoing investigation into BLOC1S2 not only elucidates its role in cellular processes but also contributes to broader research efforts aimed at unraveling the complexities of organelle biogenesis and disease pathogenesis.
