Analytical Data
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Gene name
GIOT-1
- Application
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Alternative Names
ZNF461; GIOT1Zinc finger protein 461; Gonadotropin-inducible ovary transcription repressor 1; GIOT-1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TAF7
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Expression Region
1-563aa
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AA Sequence
MAHELVMFRD VAIDVSQEEW ECLNPAQRNL YKEVMLENYS NLVSLGLSVS KPAVISSLEQ GKEPWMVVRE ETGRWCPGTW KTWGFHNNFL DNNEATDINA DLASRDEPQK LSPKRDIYET ELSQWVNMEE FKSHSPERSI FSAIWEGNCH FEQHQGQEEG YFRQLMINHE NMPIFSQHTL LTQEFYDREK ISECKKCRKI FSYHLFFSHH KRTHSKELSE CKECTEIVNT PCLFKQQTIQ NGDKCNECKE CWKAFVHCSQ LKHLRIHNGE KRYECNECGK AFNYGSELTL HQRIHTGEKP YECKECGKAF RQRSQLTQHQ RLHTGEKPYE CKQCGKAFIR GFQLTEHLRL HTGEKPYECK ECGKTFRHRS HLTIHQRIHT GEKPYECREC GKAFSYHSSF SHHQKIHSGK KPYECHECGK AFCDGLQLTL HQRIHTGEKP YECKECGKTF RQCSHLKRHQ RIHTGEKPHE CMICGKAFRL HSHLIQHQRI HTGEKPYECK ECGKAFSYHS SFSHHQRIHS GKKPYQCGKA FNHRLQLNLH QTLHTGEKPV RFPLLPPHPS LAS
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Molecular Weight
66.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GIOT-1, a novel recombinant protein, has garnered significant attention due to its potential applications in both basic research and therapeutic fields. This protein is derived from a unique gene sequence identified in specific organisms, which suggests its involvement in critical biological processes. Researchers have been particularly interested in GIOT-1 for its potential role in cellular signaling and regulation, contributing to fundamental understanding of various physiological mechanisms. The advances in recombinant DNA technology have facilitated the production of GIOT-1 in higher yields, allowing for detailed structural and functional analyses. Early studies indicate that GIOT-1 may play a role in stress responses and metabolic pathways, which could be pivotal for developing targeted therapies for diseases related to metabolic dysfunctions. Furthermore, its potential as a biomarker in disease diagnostics is being explored, emphasizing the need for detailed characterization and understanding of its functional properties. Overall, the investigation of GIOT-1 not only promises to provide insights into fundamental biological processes but also presents opportunities for novel therapeutic approaches in clinical settings.











