Cat: PA2000-7908

Recombinant Human GAS2L3 Protein,GST

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Analytical Data

  • Gene name

    GAS2L3

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    GA2L3_HUMAN; GAS2 like protein 3; GAS2-like protein 3; GAS2L3; Gm240; Growth arrest specific 2 like 3; Growth arrest specific protein 2 like 3; Growth arrest-specific protein 2-like 3

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q86XJ1

  • Expression Region

    1-694aa

  • AA Sequence

    MQPAIQVWFGEDLPLSPRSPLTPRHGPGLANVCQYDEWIAVRHEATLLPMQEDLSIWLSGLLGIKVKAEKLLEELDNGVLLCQLIDVLQNMVKTCNSEESGNFPMRKVPCKKDAASGSFFARDNTANFLHWCRDIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLNTSGPEDSISIPKSCCRHEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGDKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPQPPEMNPLSAVNMFQKQNSKPSVPVSIPKSKEKQGRPPGALVPASSLKGGNLGSMSVRSKLPNSPAASSHPKLKSSKGITKKPQAPSNNASSSLASLNPVGKNTSSPALPRTAPCISESPRKCISSPNTPKAKVIPAQNSADLPESTLLPNKCSGKTQPKYLKHNHISSRDNAVSHLAAHSNSSSKCPKLPKANIPVRPKPSFQSSAKMTKTSSKTIATGLGTQSQPSDGAPQAKPVPAQKLKSALNLNQPVSVSSVSPVKATQKSKDKNIVSATKKQPQNKSAFQKTGPSSLKSPGRTPLSIVSLPQSSTKTQTAPKSAQTVAKSQHSTKGPPRSGKTPASIRKPPSSVKDADSGDKKPTAKKKEDDDHYFVMTGSKKPRK

  • Molecular Weight

    101.6 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

GAS2L3 (Growth Arrest-Specific 2 Like 3) is a member of the GAS2 gene family, which has been implicated in various cellular processes, including growth arrest, differentiation, and apoptosis. Its role in these biological processes has garnered interest in the context of cancer and developmental disorders. Previous studies have suggested that GAS2L3 may influence cytoskeletal organization and cell signaling pathways, highlighting its potential as a regulatory molecule in cellular functions. The restructuring of the cytoskeleton and interactions with cellular membranes has led researchers to investigate GAS2L3 as a possible biomarker and therapeutic target in tumorigenesis. Understanding the structure-function relationship of GAS2L3 through the expression of recombinant proteins is essential for elucidating its biological functions. By generating GAS2L3 recombinant proteins, researchers aim to explore its molecular interactions, post-translational modifications, and impact on cell behavior, which can provide insights into its roles in disease mechanisms. The study of GAS2L3 not only contributes to the broader comprehension of GAS2 family members but could also reveal novel therapeutic strategies for cancers and other pathologies associated with aberrant growth and cellular signaling.

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