Analytical Data
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Gene name
LTBP2
- Application
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Alternative Names
LTBP2；C14orf141；LTBP3；Latent-transforming growth factor beta-binding Protein 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q14767
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Expression Region
全长
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AA Sequence
full
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LTBP2 (Latent TGF-beta Binding Protein 2) is a critical extracellular matrix protein that plays a vital role in the regulation of TGF-beta (Transforming Growth Factor-beta) signaling, which is essential for various biological processes, including cell proliferation, differentiation, and extracellular matrix formation. Research has highlighted the significance of LTBP2 in tissue development, repair, and fibrosis, as it helps in the deposition and activation of TGF-beta in the extracellular matrix. Abnormalities in LTBP2 expression and function have been linked to several pathological conditions, including Marfan syndrome and other connective tissue disorders, making it an important target for therapeutic intervention. The recombinant LTBP2 protein has been studied to elucidate its structural characteristics and functional roles, providing insights into TGF-beta regulation mechanisms. Additionally, understanding the interactions between LTBP2 and other molecular pathways involved in cell signaling can contribute to the development of new strategies for treating diseases associated with TGF-beta dysregulation. Overall, the investigation of recombinant LTBP2 not only enhances our comprehension of its biological functions but also opens avenues for novel therapeutic approaches in managing diseases related to extracellular matrix and TGF-beta signaling.
