Analytical Data
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Gene name
FASTKD3
- Application
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Alternative Names
FASTKD3FAST kinase domain-containing protein 3; mitochondrial
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q14CZ7
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Expression Region
1-662aa
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AA Sequence
MALITLRKNLYRLSDFQMHRALAALKNKPLNHVHKVVKERLCPWLCSRQPEPFGVRFHHAHCKKFHSKNGNDLHPLGGPVFSQVSDCDRLEQNVKNEESQMFYRRLSNLTSSEEVLSFISTMETLPDTMAAGALQRICEVEKKDGDQGLPKEILENSIFQALCFQFEKEPSQLSNTSLVTALQALILLHVDPQSSLLLNLVAECQNRLRKGGMEVRNLCILGESLITLHSSGCVTLELIINQLQGEKLETFTPEDIVALYRILQACTEKVDEHQTFLNKINNFSLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTNEELRRVLEAFIYFGHHDTFFTKALEHRVAAVCLTLDPEVVCRVMEYCSRELILSKPILNAVAETFVCQTEKFSPRQISALMEPFGKLNYLPPNASALFRKLENVLFTHFNYFPPKSLLKLLHSCSLNECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFLASVLECPFYKGPKLLPKYQVKSFLTPCCSLETPVDSQLYRYVKIGLTNLLGARLYFAPKVLTPYCYTIDVEIKLDEEGFVLPSTANEDIHKRIALCIDGPKRFCSNSKHLLGKEAIKQRHLQLLGYQVVQIPYHEIGMLKSRRELVEYLQRKLFSQNTVHWLQE
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Molecular Weight
72.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FASTKD3 is a member of the FASTK family of proteins, which play critical roles in the regulation of mitochondrial gene expression and protein synthesis. The research on FASTKD3 has gained momentum due to its unique function in mitochondrial biology and its potential implications in human health and disease. Recent studies suggest that FASTKD3 is involved in the modulation of mitochondrial RNA stability, translation, and the maintenance of mitochondrial integrity, making it essential for cellular energy metabolism. Abnormalities in mitochondria are linked to a variety of disorders, including neurodegenerative diseases, diabetes, and cancer, highlighting the importance of understanding the mechanisms by which FASTKD3 operates. Additionally, FASTKD3 has been shown to interact with several mitochondrial proteins and complexes, influencing various mitochondrial pathways. The ongoing research aims to elucidate the specific role of FASTKD3 in mitochondrial function, its interactions with other biomolecules, and its potential as a therapeutic target for mitochondrial-related diseases. As researchers continue to explore the diverse functions of FASTKD3, it may provide insights into novel treatment strategies and interventions that could benefit patients suffering from mitochondrial dysfunction.
