Analytical Data
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Gene name
TTC14
- Application
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Alternative Names
DKFZp313M1015; DRDL5813; FLJ00166; KIAA1980; OTTHUMP00000212531; PRO19630; Tetratricopeptide repeat domain 14; Tetratricopeptide repeat Protein 14; TPR repeat Protein 14; Ttc14; TTC14_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96N46
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Expression Region
1-770 aa
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AA Sequence
MDRDLLRQSL NCHGSSLLSL LRSEQQDNPH FRSLLGSAAE PARGPPPQHP LQGRKEKRVD NIEIQKFISK KADLLFALSW KSDAPATSEI NEDSEDHYAI MPPLEQFMEI PSMDRRELFF RDIERGDIVI GRISSIREFG FFMVLICLGS GIMRDIAHLE ITALCPLRDV PSHSNHGDPL SYYQTGDIIR AGIKDIDRYH EKLAVSLYSS SLPPHLSGIK LGVISSEELP LYYRRSVELN SNSLESYENV MQSSLGFVNP GVVEFLLEKL GIDESNPPSL MRGLQSKNFS EDDFASALRK KQSASWALKC VKIGVDYFKV GRHVDAMNEY NKALEIDKQN VEALVARGAL YATKGSLNKA IEDFELALEN CPTHRNARKY LCQTLVERGG QLEEEEKFLN AESYYKKALA LDETFKDAED ALQKLHKYMQ KSLELREKQA EKEEKQKTKK IETSAEKLRK LLKEEKRLKK KRRKSTSSSS VSSADESVSS SSSSSSSGHK RHKKHKRNRS ESSRSSRRHS SRASSNQIDQ NRKDECYPVP ANTSASFLNH KQEVEKLLGK QDRLQYEKTQ IKEKDRCPLS SSSLEIPDDF GGRSEDPRDF YNSYKTQAGS SKTEKPYKSE RHFSSRRNSS DSFCRNSEDK IYGYRRFEKD IEGRKEHYRR WEPGSVRHST SPASSEYSWK SVEKYKKYAH SGSRDFSRHE QRYRLNTNQG EYEREDNYGE DIKTEVPEED ALSSKEHSES SVKKNLPQNL LNIFNQIAEF EKEKGNKSKN
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Molecular Weight
88.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TTC14, a member of the tetratricopeptide repeat (TPR) family of proteins, has garnered attention in recent years due to its potential roles in cellular processes such as protein-protein interactions, cellular signaling, and the regulation of gene expression. Research has indicated that TTC14 may be involved in the modulation of various oncogenic pathways, making it a candidate for further investigation in cancer biology. Furthermore, studies suggest that TTC14 may play a crucial role in the cellular response to stress and the maintenance of proteostasis, which is vital for cell survival under adverse conditions. The reconstitution and characterization of TTC14 as a recombinant protein allow for a deeper understanding of its structure-function relationships and interactions with other cellular components. Such studies are essential for elucidating the biochemical mechanisms underpinning its roles in cellular physiology and pathology. As researchers explore the therapeutic potential of targeting TTC14 in disease contexts, including cancer and neurodegenerative disorders, the development of TTC14 recombinant protein offers a valuable tool for both basic research and potential clinical applications.
