Analytical Data
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基因名
C2CD3
- Application
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别名
C2CD3；C2 domain-containing Protein 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q4AC94
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C2CD3, or "C2 calcium-dependent domain-containing 3," is a protein that plays a critical role in cellular processes such as cilia formation and intracellular transport. Its involvement in various biological functions, notably in the development of ciliated cells, has attracted attention in the context of human diseases, including ciliopathies, which are disorders caused by dysfunctional cilia. Research has shown that mutations in the C2CD3 gene can lead to impaired cilia structure and function, contributing to health issues such as respiratory problems, infertility, and developmental disorders. Given the essential role of cilia in signaling pathways and maintaining homeostasis, understanding the structure and function of the C2CD3 protein is paramount. Recent studies have focused on elucidating the molecular mechanisms underlying C2CD3's role in cilia assembly and maintenance, as well as its interactions with other protein complexes. The development of recombinant C2CD3 proteins has enabled researchers to perform functional assays and explore potential therapeutic avenues for ciliopathy-related conditions. Overall, ongoing investigations into C2CD3 not only enhance our understanding of fundamental cellular biology but also pave the way for potential interventions in cilia-related diseases.
