Analytical Data
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基因名
TTC12
- Application
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别名
TTC12; Tetratricopeptide repeat Protein 12; TPR repeat Protein 12
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H892
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表达区间
1-705 aa
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氨基酸序列
MDADKEKDLQ KFLKNVDEIS NLIQEMNSDD PVVQQKAVLE TEKRLLLMEE DQEEDECRTT LNKTMISPPQ TAMKSAEEIN SEAFLASVEK DAKERAKRRR ENKVLADALK EKGNEAFAEG NYETAILRYS EGLEKLKDMK VLYTNRAQAY MKLEDYEKAL VDCEWALKCD EKCTKAYFHM GKANLALKNY SVSRECYKKI LEINPKLQTQ VKGYLNQVDL QEKADLQEKE AHELLDSGKN TAVTTKNLLE TLSKPDQIPL FYAGGIEILT EMINECTEQT LFRMHNGFSI ISDNEVIRRC FSTAGNDAVE EMVCVSVLKL WQAVCSRNEE NQRVLVIHHD RARLLAALLS SKVLAIRQQS FALLLHLAQT ESGRSLIINH LDLTRLLEAL VSFLDFSDKE ANTAMGLFTD LALEERFQVW FQANLPGVLP ALTGVLKTDP KVSSSSALCQ CIAIMGNLSA EPTTRRHMAA CEEFGDGCLS LLARCEEDVD LFREVIYTLL GLMMNLCLQA PFVSEVWAVE VSRRCLSLLN SQDGGILTRA AGVLSRTLSS SLKIVEEALR AGVVKKMMKF LKTGGETASR YAIKILAICT NSYHEAREEV IRLDKKLSVM MKLLSSEDEV LVGNAALCLG NCMEVPNVAS SLLKTDLLQV LLKLAGSDTQ KTAVQVNAGI ALGKLCTAEP RFAAQLRKLH GLEILNSTMK YISDS
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分子量
78.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TTC12, or tetratricopeptide repeat protein 12, has garnered increasing attention in the field of molecular biology and genetics due to its potential implications in various biological processes and disease states. This protein contains a series of tetratricopeptide repeats, which are known to mediate protein-protein interactions, suggesting a crucial role in cellular signaling and regulation. Initial studies have linked TTC12 to immune response modulation, with implications for autoimmune diseases, where dysregulation of immune signaling pathways is a key feature. Additionally, TTC12 has been implicated in certain cancers, indicating its potential as a biomarker or therapeutic target. The research surrounding TTC12 focuses on elucidating its functional mechanisms, interactions with other proteins, and the pathways it influences. Understanding how TTC12 operates at the molecular level could provide insights into its role in health and disease, paving the way for novel therapeutic interventions. The structural and functional characterization of TTC12, especially through recombinant protein studies, is essential to clarify its contributions in various cellular contexts and explore its potential as a target for drug development in diseases such as cancer and autoimmune disorders.
