Analytical Data
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Gene name
ZNF558
- Application
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Alternative Names
FLJ30932 ; Zinc finger Protein 558; ZN558_HUMAN; ZNF558
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96NG5
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Expression Region
1-402 aa
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AA Sequence
MAAVILPSTAAPSSLFPASQQKGHTQGGELVNELLTSWLRGLVTFEDVAVEFTQEEWALLDPAQRTLYRDVMLENCRNLASLGCRVNKPSLISQLEQDKKVVTEERGILPSTCPDLETLLKAKWLTPKKNVFRKEQSKGVKTERSHRGVKLNECNQCFKVFSTKSNLTQHKRIHTGEKPYDCSQCGKSFSSRSYLTIHKRIHNGEKPYECNHCGKAFSDPSSLRLHLRIHTGEKPYECNQCFHVFRTSCNLKSHKRIHTGENHHECNQCGKAFSTRSSLTGHNSIHTGEKPYECHDCGKTFRKSSYLTQHVRTHTGEKPYECNECGKSFSSSFSLTVHKRIHTGEKPYECSDCGKAFNNLSAVKKHLRTHTGEKPYECNHCGKSFTSNSYLSVHKRIHNRWI
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Molecular Weight
72.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF558, a member of the zinc finger protein family, has gained attention due to its potential roles in gene regulation and development. This protein is characterized by its multiple zinc finger motifs, which facilitate DNA binding and are critical for transcriptional modulation. Preliminary studies suggest that ZNF558 may be involved in various biological processes, including cellular differentiation, apoptosis, and responses to environmental stimuli. Its expression patterns have been linked to certain developmental stages and specific tissues, indicating its regulatory significance. Moreover, alterations in ZNF558 expression have been associated with various diseases, including cancer, suggesting that it may function as a tumor suppressor or an oncogene depending on the context. The construction and characterization of recombinant ZNF558 protein allow researchers to study its biochemical properties, interactions with DNA and other proteins, and its impact on cellular pathways. Understanding the functional mechanisms of ZNF558 can provide insights into its role in health and disease, potentially leading to novel therapeutic strategies. Thus, the study of ZNF558 recombinant protein represents a crucial step in elucidating the complex regulatory networks governed by zinc finger proteins in the genome.
