Cat: PA2000-7556

Recombinant Human FAM80A Protein,GST

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Analytical Data

  • Gene name

    FAM80A

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    RIMKLA; FAM80A; N-acetylaspartylglutamate synthase A; NAAG synthetase A; NAAGS; EC 6.3.2.41; N-acetylaspartylglutamylglutamate synthase A; EC 6.3.2.42; Ribosomal protein S6 modification-like protein A

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8IXN7

  • Expression Region

    1-350aa

  • AA Sequence

    MDQIAVTIVGGHLGLQLNQKALTTFPDVVLVRVPTPSVQSDSDITVLRHLEKLGCRLVNRPQSILNCINKFWTFQELAGHGVPMPDTFSYGGHEDFSKMIDEAEPLGYPVVVKSTRGHRGKAVFLARDKHHLSDICHLIRHDVPYLFQKYVKESHGKDIRVVVVGGQVIGSMLRCSTDGRMQSNCSLGGVGVKCPLTEQGKQLAIQVSNILGMDFCGIDLLIMDDGSFVVCEANANVGFLAFDQACNLDVGGIIADYTMSLLPNRQTGKMAVLPGLSSPREKNEPDGCASAQGVAESVYTINSGSTSSESEPELGEIRDSSASTMGAPPSMLPEPGYNINNRIASELKLK

  • Molecular Weight

    64.2 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

FAM80A, or Family with Sequence Similarity 80A, is a protein that has garnered interest in the field of molecular biology due to its potential roles in various cellular processes, including cell proliferation, differentiation, and apoptosis. Initial studies suggested that FAM80A may be involved in cancer progression, as its expression levels appear to be dysregulated in several malignancies. Furthermore, recent research has indicated that FAM80A could play a critical role in the regulation of key signaling pathways, such as the PI3K/AKT and MAPK pathways, which are commonly implicated in tumorigenesis. The study of recombinant FAM80A protein is essential for elucidating its biological functions and interactions at the molecular level. By producing and characterizing this recombinant protein, researchers aim to explore its structural properties, post-translational modifications, and interaction with other proteins. This understanding may contribute to the development of novel therapeutic strategies targeting FAM80A-related pathways in cancer and other diseases. As such, investigating the recombinant FAM80A protein will provide valuable insights into its roles in cellular signaling and may highlight its significance as a potential biomarker or therapeutic target in malignancies.

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