Analytical Data
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基因名
MRC1
- Application
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别名
MRC1；CLEC13D；CLEC13DL；MRC1L1；Macrophage mannose receptor 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P22897
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表达区间
655-1213aa
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氨基酸序列
RTSLCFKLYAKGKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQKGQTPKPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGLLISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINCGYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLDGYWKTAHCNESFYFLCK
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分子量
69.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRC1 (Macrophage Receptor with a C-lectin domain 1) is a receptor predominantly expressed in macrophages that plays a critical role in mediating immune responses and tissue homeostasis. It is known for its ability to recognize and bind glycoproteins and polysaccharides, thereby facilitating the phagocytosis of pathogens and apoptotic cells. Research on recombinant MRC1 protein has gained momentum in recent years due to its potential applications in immunotherapy and vaccine development. Understanding the structure and function of MRC1 can help elucidate its role in modulating immune responses, particularly in the context of infectious diseases and cancer. The recombinant production of MRC1 allows for detailed studies on its ligand interactions, signaling pathways, and its influence on macrophage polarization. Furthermore, characterizing MRC1's binding properties can provide insights into how it can be utilized as a target for drug delivery systems or as a biomarker for various diseases. As the field of immunology continues to advance, the exploration of MRC1 recombinant protein not only enhances our knowledge of macrophage biology but also holds promise for developing novel therapeutic strategies aimed at manipulating immune responses for better health outcomes.
