Cat: PA1000-8439

Recombinant Human MRC2 Protein,His

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Analytical Data

  • 基因名

    MRC2

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    MRC2;CLEC13E;ENDO180;KIAA0709;C-type mannose receptor 2

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9UBG0

  • 表达区间

    105-214aa

  • 氨基酸序列

    ASLGMYECDREALNLRWHCRTLGDQLSLLLGARTSNISKPGTLERGDQTR SGQWRIYGSEEDLCALPYHEVYTIQGNSHGKPCTIPFKYDNQWFHGCTST GREDGHLWCA

  • 分子量

    38 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

MRC2, also known as the mannose receptor C-type 2, is a crucial protein involved in various biological processes, including immune response and tissue remodeling. Its role as a receptor for extracellular matrix components and as a mediator of macrophage and dendritic cell functions has garnered significant interest in recent years. Research indicates that MRC2 is implicated in the uptake of glycoproteins and glycosylated ligands, influencing the phagocytosis of pathogens and cellular debris, thus contributing to homeostasis and inflammation. Moreover, aberrations in MRC2 expression have been associated with various diseases, including fibrosis, cancer, and autoimmune disorders, highlighting its potential as a therapeutic target. The structural characteristics and functional mechanisms of MRC2 must be thoroughly understood to exploit its capabilities in clinical applications. Consequently, the study of MRC2 recombinant proteins has become essential for elucidating its role in pathophysiology and exploring innovative treatments through targeted therapies. This research can also lead to advancements in vaccine development, enhancing the body’s ability to mount effective immune responses against infectious diseases. Understanding MRC2's interactions at the molecular level will ultimately contribute to the broader field of immunology and the development of new biopharmaceuticals, positioning MRC2 as a promising candidate for future therapeutic interventions.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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