Analytical Data
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基因名
ZNF446
- Application
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别名
ZNF446; ZKSCAN20Zinc finger Protein 446; Zinc finger Protein with KRAB and SCAN domains 20
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NWS9
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表达区间
1-450 aa
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氨基酸序列
MPSPLGPPCLPVMDPETTLEEPETARLRFRGFCYQEVAGPREALARLRELCCQWLQPEAHSKEQMLEMLVLEQFLGTLPPEIQAWVRGQRPGSPEEAAALVEGLQHDPGQLLGWITAHVLKQEVLPAAQKTEEPLGSPHPSGTVESPGEGPQDTRIEGSVQLSCSVKEEPNVDGQEVAPSSPPLAAQSPEGNHGHQEPASTSFHPPRIQEEWGLLDRSQKELYWDAMLEKYGTVVSLGLPPHQPEAQAQSELGMLLTGTGVCRSLRSGNESEGPPGCPEAQPPQGPGPAAWEGLSGAATPAPTVRPGTPPVPTQPTPAETRLEPAATPRKPYTCEQCGRGFDWKSVFVIHHRTHTSGPGVQSPGLATGESTEKPPQGEVAFPHHPRRSLTGPRSYPCEECGCSFSWKSQLVIHRKSHTGQRRHFCSDCGRAFDWKSQLVIHRKGHRPEVP
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分子量
75.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF446, a member of the Krüppel-type zinc finger protein family, has garnered attention in recent years due to its potential roles in transcriptional regulation, cellular differentiation, and development. Studies suggest that ZNF446 may play a critical role in various biological processes, including stem cell maintenance and tissue homeostasis, owing to its ability to interact with DNA and other proteins within the nucleus. Dysregulation of ZNF446 expression has been implicated in several diseases, including cancer, highlighting its importance as a potential biomarker and therapeutic target. The exploration of ZNF446 recombinant protein is crucial for elucidating its functional mechanisms, enabling the study of its binding affinities and interactions with specific DNA sequences or other protein partners. This knowledge could enhance our understanding of gene regulatory networks and contribute to the development of novel strategies for disease intervention. Thus, the production and characterization of ZNF446 recombinant protein represent a significant step towards unraveling its biological significance and therapeutic potential.
