Cat: PAX2000-12838

Recombinant Human ZNF354A Protein,His

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Analytical Data

  • Gene name

    ZNF354A

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ZNF354A; EZNF; HKL1; TCF17; Zinc finger Protein 354A; Transcription factor 17; TCF-17; Zinc finger Protein eZNF

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    O60765

  • Expression Region

    1-605 aa

  • AA Sequence

    MAAGQREARP QVSLTFEDVA VLFTRDEWRK LAPSQRNLYR DVMLENYRNL VSLGLPFTKP KVISLLQQGE DPWEVEKDGS GVSSLGSKSS HKTTKSTQTQ DSSFQGLILK RSNRNVPWDL KLEKPYIYEG RLEKKQDKKG SFQIVSATHK KIPTIERSHK NTELSQNFSP KSVLIRQQIL PREKTPPKCE IQGNSLKQNS QLLNQPKITA DKRYKCSLCE KTFINTSSLR KHEKNHSGEK LFKCKECSKA FSQSSALIQH QITHTGEKPY ICKECGKAFT LSTSLYKHLR THTVEKSYRC KECGKSFSRR SGLFIHQKIH AEENPCKYNP GRKASSCSTS LSGCQRIHSR KKSYLCNECG NTFKSSSSLR YHQRIHTGEK PFKCSECGRA FSQSASLIQH ERIHTGEKPY RCNECGKGFT SISRLNRHRI IHTGEKFYNC NECGKALSSH STLIIHERIH TGEKPCKCKV CGKAFRQSSA LIQHQRMHTG ERPYKCNECG KTFRCNSSLS NHQRIHTGEK PYRCEECGIS FGQSSALIQH RRIHTGEKPF KCNTCGKTFR QSSSRIAHQR IHTGEKPYEC NTCGKLFNHR SSLTNHYKIH IEEDP

  • Molecular Weight

    69.2 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ZNF354A, a member of the zinc finger protein family, has garnered attention due to its potential roles in various biological processes, including gene regulation and cellular differentiation. This protein is characterized by its unique zinc finger motifs, which facilitate interactions with nucleic acids and other proteins, making it a critical player in transcriptional regulation. Recent studies have suggested that ZNF354A may be implicated in developmental pathways and could be associated with certain diseases, including cancer. Given its multifunctional nature, the investigation of recombinant ZNF354A has emerged as a promising approach to elucidate its biological mechanisms and functions. Producing purified recombinant ZNF354A allows researchers to conduct biochemical assays, structural studies, and functional analyses, which are essential to understand how this protein influences cellular processes. Furthermore, the study of ZNF354A at the molecular level may provide insights into its potential as a therapeutic target, opening avenues for novel treatments for diseases linked to its dysregulation. As such, the recombinant expression and characterization of ZNF354A are crucial for advancing our understanding of its role in health and disease.

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