Analytical Data
-
Gene name
TRBV3-1
- Application
-
Alternative Names
T cell receptor beta variable 3-1
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
A0A576
-
Expression Region
1-315 aa
-
AA Sequence
MGCRLLCCVVFCLLQAGPLDTAVSQTPKYLVTQMGNDKSIKCEQNLGHDTMYWYKQDSKKFLKIMFSYNNKELIINETVPNRFSPKSPDKAHLNLHINSLELGDSAVYFCASSPIGATSSSYNEQFFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVSTDPQPLKEQPALNDSRYCLSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRADCGFTSESYQQGVLSATILYEILLGKATLYAVLVSALVLMAMVKRKDSRG
-
Molecular Weight
61.7 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TRBV3-1, a member of the T-cell receptor beta (TCRβ) gene family, has garnered significant attention in the field of immunology due to its role in T-cell development and immune response. T cells are crucial for adaptive immunity, and their activation is mediated by TCRs that recognize antigens presented by Major Histocompatibility Complex (MHC) molecules. The study of TRBV3-1 is particularly important because variations in the TCR repertoire can influence susceptibility to diseases, including autoimmune disorders and cancers. Recent advances in high-throughput sequencing and bioinformatics have enabled researchers to explore the diversity and specificity of TCRs, including TRBV3-1, in different contexts such as viral infections and tumor microenvironments. Furthermore, the potential of TRBV3-1 in immunotherapy, particularly in engineered T-cell therapies, has made it a focus of targeted studies aimed at harnessing its specificity for therapeutic applications. Understanding the structure, function, and interaction of TRBV3-1 with its ligands is essential for the development of novel immunotherapeutic strategies that can enhance T cell-mediated responses against malignancies and infections.
