Analytical Data
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基因名
TRBV5-4
- Application
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别名
T cell receptor beta variable 5-4
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A0A0C4DH59
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表达区间
1-308 aa
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氨基酸序列
MGPGLLCWALLCLLGAGSVETGVTQSPTHLIKTRGQQVTLRCSSQSGHNTVSWYQQALGQGPQFIFQYYREEENGRGNFPPRFSGLQFPNYSSELNVNALELDDSALYLCASSIAREQFFGPGTRLTVLEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVSTDPQPLKEQPALNDSRYCLSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRADCGFTSESYQQGVLSATILYEILLGKATLYAVLVSALVLMAMVKRKDSRG
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分子量
60.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TRBV5-4 is a member of the T-cell receptor beta (TCRB) variable gene segment family, which plays a crucial role in the adaptive immune response. Recent studies have indicated that TRBV5-4 is associated with recognition of specific antigens, particularly in the context of viral infections and certain cancers. Its distinct variability provides insights into the diversity of T-cell responses, making it a target of interest in immunology and vaccine development. Researchers investigate the recombinant expression of TRBV5-4 proteins to better understand how T-cells recognize pathogens and to develop targeted therapies. Additionally, TRBV5-4 has shown potential in identifying tumor-specific antigens, suggesting its utility in cancer immunotherapy. The recombinant proteins also serve as critical tools for the development of T-cell receptor therapies, allowing for custom-engineered T-cells that can effectively target malignant cells or enhance immune responses against chronic infections. Overall, the study of TRBV5-4 recombinant proteins is contributing to advances in immunotherapy, providing valuable insights into T-cell functionality and offering avenues for innovative therapeutic strategies.
