Cat: PAX2000-12836

Recombinant Human ZNF34 Protein,His

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Analytical Data

  • Gene name

    ZNF34

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Zinc finger Protein KOX32; ZNF34; ZNF34_HUMAN

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8IZ26

  • Expression Region

    1-560 aa

  • AA Sequence

    MLLLLSDQLL LTALRKPNPQ AMAALFLSAP PQAEVTFEDV AVYLSREEWG RLGPAQRGLY RDVMLETYGN LVSLGVGPAG PKPGVISQLE RGDEPWVLDV QGTSGKEHLR VNSPALGTRT EYKELTSQET FGEEDPQGSE PVEACDHISK SEGSLEKLVE QRGPRAVTLT NGESSRESGG NLRLLSRPVP DQRPHKCDIC EQSFEQRSYL NNHKRVHRSK KTNTVRNSGE IFSANLVVKE DQKIPTGKKL HYCSYCGKTF RYSANLVKHQ RLHTEEKPYK CDECGKAFSQ SCEFINHRRM HSGEIPYRCD ECGKTFTRRP NLMKHQRIHT GEKPYKCGEC GKHFSAYSSL IYHQRIHTGE KPYKCNDCGK AFSDGSILIR HRRTHTGEKP FECKECGKGF TQSSNLIQHQ RIHTGEKPYK CNECEKAFIQ KTKLVEHQRS HTGEKPYECN DCGKVFSQST HLIQHQRIHT GEKPYKCSEC GKAFHNSSRL IHHQRLHHGE KPYRCSDCKK AFSQSTYLIQ HRRIHTGEKP YKCSECGKAF RHSSNMCQHQ RIHLREDFSM

  • Molecular Weight

    64 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ZNF34, a member of the zinc finger protein family, is implicated in various biological processes, including transcriptional regulation and chromatin remodeling. Recent studies have highlighted the potential role of ZNF34 in cellular differentiation, development, and stress responses. As a transcription factor, ZNF34 binds to specific DNA sequences, influencing gene expression patterns crucial for cell fate and function. The interest in ZNF34 has surged due to its association with various diseases, including cancer, where alterations in its expression levels may contribute to tumorigenesis. Researchers have been focusing on the recombinant production of ZNF34 to facilitate detailed studies of its structure and function. Recombinant protein expression allows for the generation of large quantities of purified ZNF34, enabling the investigation of its biochemical properties, interaction partners, and molecular mechanisms. Furthermore, understanding ZNF34’s function at a molecular level could provide insights into its regulatory roles within cells, potentially leading to novel therapeutic strategies targeting related pathways. Overall, the study of recombinant ZNF34 not only enhances our comprehension of its biological significance but also paves the way for future research aimed at elucidating the broader implications of zinc finger proteins in health and disease.

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