Analytical Data
-
Gene name
ZNF345
- Application
-
Alternative Names
Zinc finger Protein HZF10; ZN345_HUMAN; ZNF345
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q14585
-
Expression Region
1-488 aa
-
AA Sequence
MENLTKHSIE CSSFRGDWEC KNQFERKQGS QEGHFSEMIF TPEDMPTFSI QHQRIHTDEK LLECKECGKD FSFVSVLVRH QRIHTGEKPY ECKECGKAFG SGANLAYHQR IHTGEKPFEC KECGKAFGSG SNLTHHQRIH TGEKPYECKE CGKAFSFGSG LIRHQIIHSG EKPYECKECG KSFSFESALI RHHRIHTGEK PYECIDCGKA FGSGSNLTQH RRIHTGEKPY ECKACGMAFS SGSALTRHQR IHTGEKPYIC NECGKAFSFG SALTRHQRIH TGEKPYVCKE CGKAFNSGSD LTQHQRIHTG EKPYECKECE KAFRSGSKLI QHQRMHTGEK PYECKECGKT FSSGSDLTQH HRIHTGEKPY ECKECGKAFG SGSKLIQHQL IHTGERPYEC KECGKSFSSG SALNRHQRIH TGEKPYECKE CGKAFYSGSS LTQHQRIHTG EKLYECKNCG KAYGRDSEFQ QHKKSHNGKK LCELETIN
-
Molecular Weight
55.3 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF345, a member of the zinc-finger protein family, has garnered significant interest in the field of molecular biology due to its potential role in gene regulation and cellular processes. Zinc-finger proteins are characterized by their ability to bind DNA through zinc coordination, which allows them to influence transcriptional activity. Recent studies have suggested that ZNF345 may be involved in critical biological functions, including cell differentiation, proliferation, and the maintenance of genomic stability. The understanding of ZNF345's mechanisms has implications for various diseases, particularly cancer, where dysregulation of zinc-finger proteins is often observed. Given the importance of ZNF345 in these processes, researchers are increasingly focusing on the production and characterization of recombinant ZNF345 proteins. This enables the investigation of its functional properties, interactions with other cellular components, and its overall role in health and disease. By employing techniques such as recombinant DNA technology, scientists aim to elucidate the structure-function relationships of ZNF345, which can provide insights into its biological significance and potential therapeutic applications. This research can pave the way for novel strategies in targeted therapies and enhance our understanding of complex regulatory networks governed by zinc-finger proteins.
