Analytical Data
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Gene name
TMIGD1
- Application
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Alternative Names
TMIGD1; TMIGD; UNQ9372/PRO34164Transmembrane and immunoglobulin domain-containing Protein 1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6UXZ0
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Expression Region
1-262 aa
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AA Sequence
MAWKSSVIMQMGRFLLLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPIIAACVVIFLTLCFGLIARRKKIMKLCMKDKDPHSETAL
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Molecular Weight
55.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TMIGD1 (Transmembrane Immunoglobulin and mucin-domain containing protein 1) is a novel protein that has garnered significant attention in the field of immunology and cancer research. As a member of the immunoglobulin superfamily, TMIGD1 is characterized by its unique structure, which includes both a transmembrane domain and a mucin-like domain, suggesting its potential role in cell adhesion and signaling processes. Initial studies have indicated that TMIGD1 plays a crucial role in regulating immune responses, particularly in T cell activation and survival. Its expression is often upregulated in various malignancies, raising questions about its involvement in tumorigenesis and immune evasion mechanisms. The growing interest in TMIGD1 also stems from its potential as a therapeutic target, as modulating its function could enhance anti-tumor immunity or improve the efficacy of existing treatments. Consequently, the generation of recombinant TMIGD1 protein has become a key focus, as it enables researchers to study its biological functions, interaction partners, and the underlying pathways it governs. By elucidating these mechanisms, the research on TMIGD1 could pave the way for novel immune-based therapies and provide deeper insights into the complexities of the tumor microenvironment and immune regulation.
