Analytical Data
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基因名
TMIGD1
- Application
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别名
TMIGD1; TMIGD; UNQ9372/PRO34164Transmembrane and immunoglobulin domain-containing Protein 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6UXZ0
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表达区间
1-262 aa
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氨基酸序列
MAWKSSVIMQMGRFLLLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPIIAACVVIFLTLCFGLIARRKKIMKLCMKDKDPHSETAL
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分子量
55.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TMIGD1 (Transmembrane Immunoglobulin and mucin-domain containing protein 1) is a novel protein that has garnered significant attention in the field of immunology and cancer research. As a member of the immunoglobulin superfamily, TMIGD1 is characterized by its unique structure, which includes both a transmembrane domain and a mucin-like domain, suggesting its potential role in cell adhesion and signaling processes. Initial studies have indicated that TMIGD1 plays a crucial role in regulating immune responses, particularly in T cell activation and survival. Its expression is often upregulated in various malignancies, raising questions about its involvement in tumorigenesis and immune evasion mechanisms. The growing interest in TMIGD1 also stems from its potential as a therapeutic target, as modulating its function could enhance anti-tumor immunity or improve the efficacy of existing treatments. Consequently, the generation of recombinant TMIGD1 protein has become a key focus, as it enables researchers to study its biological functions, interaction partners, and the underlying pathways it governs. By elucidating these mechanisms, the research on TMIGD1 could pave the way for novel immune-based therapies and provide deeper insights into the complexities of the tumor microenvironment and immune regulation.
