Cat: PAX2000-12778

Recombinant Human ZNF227 Protein,His

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Analytical Data

  • Gene name

    ZNF227

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ZNF227; Zinc finger Protein 227

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q86WZ6

  • Expression Region

    1-799 aa

  • AA Sequence

    MPSQNYDLPQ KKQEKMTKFQ EAVTFKDVAV VFSREELRLL DLTQRKLYRD VMVENFKNLV AVGHLPFQPD MVSQLEAEEK LWMMETETQR SSKHQNKMET LQKFALKYLS NQELSCWQIW KQVASELTRC LQGKSSQLLQ GDSIQVSENE NNIMNPKGDS SIYIENQEFP FWRTQHSCGN TYLSESQIQS RGKQIDVKNN LQIHEDFMKK SPFHEHIKTD TEPKPCKGNE YGKIISDGSN QKLPLGEKPH PCGECGRGFS YSPRLPLHPN VHTGEKCFSQ SSHLRTHQRI HPGEKLNRCH ESGDCFNKSS FHSYQSNHTG EKSYRCDSCG KGFSSSTGLI IHYRTHTGEK PYKCEECGKC FSQSSNFQCH QRVHTEEKPY KCEECGKGFG WSVNLRVHQR VHRGEKPYKC EECGKGFTQA AHFHIHQRVH TGEKPYKCDV CGKGFSHNSP LICHRRVHTG EKPYKCEACG KGFTRNTDLH IHFRVHTGEK PYKCKECGKG FSQASNLQVH QNVHTGEKRF KCETCGKGFS QSSKLQTHQR VHTGEKPYRC DVCGKDFSYS SNLKLHQVIH TGEKPYKCEE CGKGFSWRSN LHAHQRVHSG EKPYKCEQCD KSFSQAIDFR VHQRVHTGEK PYKCGVCGKG FSQSSGLQSH QRVHTGEKPY KCDVCGKGFR YSSQFIYHQR GHTGEKPYKC EECGKGFGRS LNLRHHQRVH TGEKPHICEE CGKAFSLPSN LRVHLGVHTR EKLFKCEECG KGFSQSARLE AHQRVHTGEK PYKCDICDKD FRHRSRLTYH QKVHTGKKL

  • Molecular Weight

    92 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ZNF227, or Zinc Finger Protein 227, is a member of the zinc finger protein family, which plays critical roles in various biological processes, including transcription regulation, DNA binding, and chromatin remodeling. Research on ZNF227 has gained interest due to its potential involvement in multiple cellular pathways and its implications in diseases such as cancer and developmental disorders. The protein's unique structural characteristics, particularly its zinc finger motifs, suggest that it may interact with specific DNA sequences or other proteins, influencing gene expression. Recent studies have indicated that ZNF227 may function as a transcription factor and is implicated in the regulation of genes associated with cell proliferation and apoptosis. Consequently, understanding the molecular mechanisms underlying ZNF227's functions is crucial for elucidating its role in health and disease. Recombinant ZNF227 protein studies enable researchers to explore its functional properties in vitro, providing insights into its interactions at the molecular level. This research is not only pivotal for understanding fundamental biological processes but also for developing potential therapeutic strategies targeting ZNF227-related pathways in diseases.

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