Analytical Data
-
Gene name
ZNF224
- Application
-
Alternative Names
BMZF 2; BMZF-2; BMZF2; Bone marrow zinc finger 2; KOX22; Zinc finger 2; bone marrow; Zinc finger Protein 224; Zinc finger Protein 233; Zinc finger Protein 255; Zinc finger Protein 27 (KOX 22); Zinc finger Protein 27; Zinc finger Protein KOX22; Zinc finger Protein ZNF255; ZN224_HUMAN; ZNF224; ZNF255; ZNF27
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9NZL3
-
Expression Region
1-707 aa
-
AA Sequence
MTTFKEAMTF KDVAVVFTEE ELGLLDLAQR KLYRDVMLEN FRNLLSVGHQ AFHRDTFHFL REEKIWMMKT AIQREGNSGD KIQTEMETVS EAGTHQEWSF QQIWEKIASD LTRSQDLMIN SSQFSKEGDF PCQTEAGLSV IHTRQKSSQG NGYKPSFSDV SHFDFHQQLH SGEKSHTCDE CGKNFCYISA LRIHQRVHMG EKCYKCDVCG KEFSQSSHLQ THQRVHTGEK PFKCVECGKG FSRRSALNVH HKLHTGEKPY NCEECGKAFI HDSQLQEHQR IHTGEKPFKC DICGKSFCGR SRLNRHSMVH TAEKPFRCDT CDKSFRQRSA LNSHRMIHTG EKPYKCEECG KGFICRRDLY THHMVHTGEK PYNCKECGKS FRWASCLLKH QRVHSGEKPF KCEECGKGFY TNSQCYSHQR SHSGEKPYKC VECGKGYKRR LDLDFHQRVH TGEKLYNCKE CGKSFSRAPC LLKHERLHSG EKPFQCEECG KRFTQNSHLH SHQRVHTGEK PYKCEKCGKG YNSKFNLDMH QKVHTGERPY NCKECGKSFG WASCLLKHQR LHSGEKPFKC EECGKRFTQN SQLHSHQRVH TGEKPYKCDE CGKGFSWSST RLTHQRRHSR ETPLKCEQHG KNIVQNSFSK VQEKVHSVEK PYKCEDCGKG YNRRLNLDMH QRVHMGEKTW KCRECDMCFS QASSLRLHQN VHVGEKP
-
Molecular Weight
82.2 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF224, or Zinc Finger Protein 224, is a member of the krüppel-like factor (KLF) family, which plays a pivotal role in gene regulation and cellular processes such as differentiation, proliferation, and apoptosis. Its unique structure, characterized by multiple zinc finger motifs, allows for specific binding to DNA and interaction with other transcription factors. Research on ZNF224 has gained interest due to its potential implications in various diseases, particularly cancer and developmental disorders. Studies suggest that ZNF224 may influence tumorigenesis by regulating the expression of key oncogenes and tumor suppressors. Additionally, its role in developmental processes indicates that it could be significant in understanding congenital anomalies. The production of recombinant ZNF224 protein enables researchers to investigate its functional properties, binding activities, and interactions with other cellular components in vitro, facilitating the exploration of its mechanisms in health and disease. Thus, ongoing research focuses on clarifying the biological functions of ZNF224, which could provide insights into targeted therapeutic strategies and biomarker development for cancer and other genetic disorders.
