Analytical Data
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基因名
ZCCHC13
- Application
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别名
ZCCHC13; Zinc finger CCHC domain-containing Protein 13
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8WW36
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表达区间
1-166 aa
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氨基酸序列
MSSKDFFACGHSGHWARGCPRGGAGGRRGGGHGRGSQCGSTTLSYTCYCCGESGRNAKNCVLLGNICYNCGRSGHIAKDCKDPKRERRQHCYTCGRLGHLARDCDRQKEQKCYSCGKLGHIQKDCAQVKCYRCGEIGHVAINCSKARPGQLLPLRQIPTSSQGMSQ
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分子量
44.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZCCHC13, a member of the zinc finger CCCH-type containing protein family, has garnered attention for its potential roles in various cellular processes, including RNA metabolism and gene regulation. Previous studies have indicated that ZCCHC13 is involved in the post-transcriptional regulation of gene expression, particularly through its interaction with RNA and other regulatory proteins. Notably, its implications in cancer biology have been highlighted, suggesting that ZCCHC13 may play a role in tumorigenesis and cell proliferation. Researchers aim to understand the structural and functional characteristics of ZCCHC13, which could reveal insights into its molecular mechanisms and wider biological significance. The recombinant expression of ZCCHC13 protein allows for detailed studies on its interactions, functions, and potential therapeutic applications. By using techniques such as crystallography and mass spectrometry, scientists are uncovering the protein's tertiary structure and binding properties, establishing a foundation for future investigations into its role in health and disease. Overall, the research on ZCCHC13 not only contributes to our understanding of RNA-binding proteins but also opens avenues for exploring new targets in cancer therapy and other disorders linked to dysregulated gene expression.
