Analytical Data
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Gene name
EFCAB7
- Application
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Alternative Names
EF hand calcium binding domain 7; EF-hand calcium-binding domain-containing protein 7; Efcab7; EFCB7_HUMAN; KIAA1799; RP4-534K7.1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
A8K855
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Expression Region
1-629aa
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AA Sequence
MAISPRSDATFSSQKSTPSESPRTKKFPLTEEEIFYMNCRAAYLTVFKSSLENIISKDQLYLALQHAGRNPSQKTINKYWTPQTAKLNFDDFCIILRKEKPTSKAELLKSFKQLDVNDDGCILHTDLYKFLTKRGEKMTREEVNAIINLADVNADGKFDYIKFCKLYMTTNEQCLKTTLEKLEVDSKLMRHQFGNHIEGSPERDPSPVPKPSPKITRKTDPETFLNKGDTRSSLLSATRKFKTSVSFIVTMGANGNRNSKLTEPNLIKDWQHMQSKGCFFLEEDGEIISHQYRMQIAQRSMVYLTIKPLNLSQVEGKPSPWLSVDTALYILKENESQANLQLVCFTELRNREVFGWTGELGPGIYWLIPSTTGCKLRKKIKPVTDEAQLVYRDETGELFLTKEFKSTLSDIFEVIDLDGNGLLSLEEYNFFELRTSGEKCDEDAWAVCRENFDTKRNELTRQGFMDLNLMEANDREGDPCDLWVTLHSMGYNKALELTEACPFVIDIYAEKCKPKIKAVHMEACSGQLEKAICKSVLSNGDAKVMDGYENIIVHTYSCDTWITSVIENKSDEKVIIHISNELSKNCINNRGLNIFAVEVGPKSTMVCQHVMPLNERQEWIYYCIYSLIS
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Molecular Weight
98.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EFCAB7 is a member of the calcium-binding EF-hand protein family, characterized by its ability to bind calcium ions, which play a crucial role in various cellular processes. The understanding of EFCAB7's function has gained attention due to its potential involvement in regulating intracellular calcium signaling pathways and its implications in various diseases, including neurodegenerative disorders and cancer. Recent studies suggest that EFCAB7 may interact with key signaling molecules, influencing cellular responses to stimuli. The recombinant expression of EFCAB7 provides an essential tool for elucidating its biochemical properties and functional roles. By producing EFCAB7 in a controlled environment, researchers can investigate its structural characteristics, calcium-binding properties, and interactions with other proteins. This research not only enhances our understanding of EFCAB7's physiological roles but also opens avenues for exploring its potential as a therapeutic target. As the field of calcium signaling continues to expand, EFCAB7 stands out as a promising candidate for further exploration, particularly in understanding its mechanistic contributions to cell signaling and its broader implications in health and disease.
