Analytical Data
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基因名
TCFL1
- Application
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别名
CFL1; HGNC11644; Protein YL-1; Swc2; TCFL1; Transcription factor like 1 (YL1); Transcription Factor Like 1; Transcription factor-like 1; Vacuolar Protein sorting 72 (yeast); Vacuolar Protein sorting 72 homolog (S. cerevisiae); Vacuolar Protein sorting associated Protein 72 homolog; Vacuolar Protein sorting-associated Protein 72 homolog; VPS72; VPS72_HUMAN; YL-1; YL1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15906
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表达区间
1-364 aa
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氨基酸序列
MSLAGGRAPR KTAGNRLSGL LEAEEEDEFY QTTYGGFTEE SGDDEYQGDQ SDTEDEVDSD FDIDEGDEPS SDGEAEEPRR KRRVVTKAYK EPLKSLRPRK VNTPAGSSQK AREEKALLPL ELQDDGSDSR KSMRQSTAEH TRQTFLRVQE RQGQSRRRKG PHCERPLTQE ELLREAKITE ELNLRSLETY ERLEADKKKQ VHKKRKCPGP IITYHSVTVP LVGEPGPKEE NVDIEGLDPA PSVSALTPHA GTGPVNPPAR CSRTFITFSD DATFEEWFPQ GRPPKVPVRE VCPVTHRPAL YRDPVTDIPY ATARAFKIIR EAYKKYITAH GLPPTASALG PGPPPPEPLP GSGPRALRQK IVIK
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分子量
40.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TCFL1, or T cell factor like 1, is a crucial transcription factor involved in various cellular processes, including T-cell development, immune response, and gene regulation. Research into TCFL1 has gained momentum due to its pivotal role in mediating signaling pathways that influence cell proliferation and differentiation. Dysregulation of TCFL1 has been implicated in several diseases, including cancers, where it contributes to tumorigenesis by altering gene expression profiles. The study of recombinant TCFL1 proteins allows researchers to elucidate its structural and functional properties, providing insights into its interactions with DNA and other proteins. Recombinant protein studies facilitate the understanding of TCFL1's role in specific pathways, serve as a basis for therapeutic interventions, and enable the development of targeted treatments for diseases where TCFL1 is misregulated. Furthermore, these investigations can aid in the identification of upstream signaling molecules that modulate TCFL1 activity, enhancing our understanding of its involvement in both normal physiology and pathophysiological conditions. Consequently, the research on TCFL1 and its recombinant protein is crucial for advancing our knowledge of immune responses and developing innovative strategies for cancer therapy and other immune-related disorders.
