Analytical Data
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Gene name
ZBTB39
- Application
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Alternative Names
ZBTB39; KIAA0352; Zinc finger and BTB domain-containing Protein 39
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15060
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Expression Region
1-712 aa
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AA Sequence
MGMRIKLQSTNHPNNLLKELNKCRLSETMCDVTIVVGSRSFPAHKAVLACAAGYFQNLFLNTGLDAARTYVVDFITPANFEKVLSFVYTSELFTDLINVGVIYEVAERLGMEDLLQACHSTFPDLESTARAKPLTSTSESHSGTLSCPSAEPAHPLGELRGGGDYLGADRNYVLPSDAGGSYKEEEKNVASDANHSLHLPQPPPPPPKTEDHDTPAPFTSIPSMMTQPLLGTVSTGIQTSTSSCQPYKVQSNGDFSKNSFLTPDNAVDITTGTNSCLSNSEHSKDPGFGQMDELQLEDLGDDDLQFEDPAEDIGTTEEVIELSDDSEDELAFGENDNRENKAMPCQVCKKVLEPNIQLIRQHARDHVDLLTGNCKVCETHFQDRNSRVTHVLSHIGIFLFSCDMCETKFFTQWQLTLHRRDGIFENNIIVHPNDPLPGKLGLFSGAASPELKCAACGKVLAKDFHVVRGHILDHLNLKGQACSVCDQRHLNLCSLMWHTLSHLGISVFSCSVCANSFVDWHLLEKHMAVHQSLEDALFHCRLCSQSFKSEAAYRYHVSQHKCNSGLDARPGFGLQHPALQKRKLPAEEFLGEELALQGQPGNSKYSCKVCGKRFAHTSEFNYHRRIHTGEKPYQCKVCHKFFRGRSTIKCHLKTHSGALMYRCTVCGHYSSTLNLMSKHVGVHKGSLPPDFTIEQTFMYIIHSKEADKNPDS
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Molecular Weight
105.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZBTB39, also known as ZNF545, is a member of the zinc finger and BTB (bric-a-brac, tramtrack, and broad complex) protein family, which plays a crucial role in various cellular processes, including transcriptional regulation, cell differentiation, and the immune response. Recent studies have highlighted the significance of ZBTB39 in cancer biology, immune system regulation, and neurological disorders. Its ability to interact with specific DNA sequences suggests a pivotal role in gene expression modulation. Overexpression or mutations in ZBTB39 have been linked to aberrant cellular behaviors, including uncontrolled proliferation and evasion of apoptosis, often seen in cancerous cells. Additionally, research indicates that ZBTB39 may participate in epigenetic regulation by influencing chromatin structure and stability. Understanding the biochemical properties and functional dynamics of recombinant ZBTB39 protein is critical for elucidating its roles in pathophysiological contexts. By studying the recombinant form of this protein, researchers aim to delineate its mechanisms and discover potential therapeutic targets. Furthermore, ZBTB39's involvement in immune regulation implies that it could be a valuable biomarker or target for immunotherapy. This underscores the need for extensive investigation into ZBTB39's structure-function relationships and interactions with other molecular players, driving forward our comprehension of its contributions to health and disease. As such, the research surrounding ZBTB39 recombinant protein is both timely and essential, aiming to uncover new insights into its biological functions and therapeutic potential.
