Analytical Data
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基因名
ZBTB37
- Application
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别名
ZBT37_HUMAN; ZBTB37; Zinc finger and BTB domain containing Protein 37; Zinc finger and BTB domain-containing Protein 37
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5TC79
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表达区间
1-361 aa
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氨基酸序列
MEKGGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHQERPPESHRVTPNLNRSLSPRHNTPKGNRRGQVSAVLDIRELSPPEESTSPQIIEPSSDVESREPILRINRAGQWYVETGVADRGGRSDDEVRVLGAVHIKTENLEEWLGPENQPSGEDGSSAEEVTAMVIDTTGHGSVGQENYTLGSSGAKVARPTSSEVDRFSPSGSVVPLTERHRARSESPGRMDEPKQPSSQVWSCGFRTALVVGGIATVYE
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分子量
66.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZBTB37, a member of the ZBTB (Zinc Finger and BTB domain-containing protein) family, has garnered attention due to its potential roles in regulating gene expression and its involvement in various biological processes, including cell proliferation and differentiation. It is characterized by a BTB/POZ domain that mediates protein-protein interactions and several zinc-finger motifs that facilitate DNA binding. Recent studies suggest that ZBTB37 may play a crucial role in the epigenetic regulation of gene expression, potentially influencing developmental pathways and immune responses. Aberrations in ZBTB37 expression have been linked to several diseases, including certain cancers, making it a target of interest in cancer research and therapeutic development. The recombinant protein has been utilized to elucidate its functional mechanisms and interactions with various cellular partners, providing insights into its role within the cellular context. Understanding the structure-function relationship of ZBTB37 could reveal novel therapeutic strategies, especially when considering its implications in tumorigenesis and immune modulation. Consequently, the study of ZBTB37 recombinant protein not only advances basic biological knowledge but also paves the way for targeted interventions in disease contexts associated with its dysregulation.
