Analytical Data
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Gene name
CCK4
- Application
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Alternative Names
CCK4；CCK4；Inactive tyrosine-Protein kinase 7
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13308
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Expression Region
31-704aa
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AA Sequence
AIVFIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFA QGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVV LKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSS KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLA PQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATV FANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEP RVFTAGSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHELVLAN IAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGY LDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYR CMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGRE KPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQI RAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDR ILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLY VVDKPVPEESEGPGSPPPYKMIQT
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Molecular Weight
77 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCK4 (Cholecystokinin-4) is a peptide that plays a crucial role in various physiological processes, particularly in the digestive system and as a neurotransmitter in the brain. It is a member of the cholecystokinin family, which is primarily involved in stimulating the gallbladder to contract and release bile, as well as promoting enzyme secretion from the pancreas. Research on CCK4 has garnered attention due to its potential implications in both digestive health and neuropsychiatric disorders. The reconstitution of CCK4 as a recombinant protein allows for detailed studies into its structure-function relationship, receptor binding characteristics, and downstream signaling pathways. Moreover, understanding the biological function of CCK4 can pave the way for therapeutic developments targeting gastrointestinal diseases, inflammatory conditions, and even psychological disorders linked to altered peptide signaling. Scientists strive to elucidate the molecular mechanisms by which CCK4 exerts its effects, considering its dual roles in endocrine and central nervous systems. Therefore, the production of CCK4 as a recombinant protein presents a valuable tool for investigating its biological activities and therapeutic potential, with implications for improving treatments for gastrointestinal and neurological conditions. As researchers continue to explore the nuances of CCK4’s interactions and functions, its role in health and disease remains a vibrant area of investigation within biomedical research.
