Analytical Data
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基因名
ZBTB34
- Application
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别名
ZBTB34; KIAA1993; Zinc finger and BTB domain-containing Protein 34
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NCN2
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表达区间
1-500 aa
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氨基酸序列
MDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEENPESRNGVKDSSFFANPVEISPPYCSQGRQPTASSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKVKMEKSDRPSCSDSSSLGDDGYHTEMVDGEQVVAVNVGSYGSVLQHAYSYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDLQGLVQGSDSEAMMNNPGYESSPRERSARGHWYPYNERLICIYCGKSFNQKGSLDRHMRLHMGITPFVCKFCGKKYTRKDQLEYHIRGHTDDKPFRCEICGKCFPFQGTLNQHLRKNHPGVAEVRSRIESPERTDVYVEQKLENDASASEMGLDSRMEIHTVSDAPD
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分子量
55 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZBTB34, a member of the ZBTB (Zinc Finger and BTB Domain Containing) family of proteins, has gained attention due to its roles in critical biological processes, including gene regulation, cellular differentiation, and immune response. Studies have indicated that ZBTB34 functions as a transcription factor, influencing the expression of target genes involved in hematopoiesis and immune functions, making it a potential player in various hematological disorders and immunological diseases. Furthermore, the protein is characterized by its zinc finger motifs, which are essential for DNA binding, and its BTB domain, which is involved in protein-protein interactions, suggesting a multifaceted role in cellular signaling and transcriptional regulation. Research into ZBTB34 recombinant proteins has emerged as a promising avenue for elucidating its mechanistic functions and biological significance. By generating these recombinant proteins, researchers aim to explore interaction dynamics with other regulatory proteins and transcriptional machinery, providing insights into how ZBTB34 contributes to cellular homeostasis and pathology. This line of investigation is particularly pertinent in the context of cancer, where dysregulation of transcription factors can lead to aberrant cell proliferation and survival. Consequently, understanding ZBTB34's function could unveil novel therapeutic targets and strategies for intervention in diseases linked to its dysregulation. Through structural and functional analyses, the study of ZBTB34 recombinant proteins is critical for advancing our knowledge of gene expression regulation and its implications in health and disease.
