Analytical Data
-
基因名
TBC1D23
- Application
-
别名
DKFZp667G062; FLJ11046; HCV non-structural protein 4A-transactivated protein 1; NS4ATP1; TBC1 domain family member 23; TBC1D23; TBC23_HUMAN
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9NUY8
-
表达区间
1-699 aa
-
氨基酸序列
MAEGEDVPPL PTSSGDGWEK DLEEALEAGG CDLETLRNII QGRPLPADLR AKVWKIALNV AGKGDSLASW DGILDLPEQN TIHKDCLQFI DQLSVPEEKA AELLLDIESV ITFYCKSRNI KYSTSLSWIH LLKPLVHLQL PRSDLYNCFY AIMNKYIPRD CSQKGRPFHL FRLLIQYHEP ELCSYLDTKK ITPDSYALNW LGSLFACYCS TEVTQAIWDG YLQQADPFFI YFLMLIILVN AKEVILTQES DSKEEVIKFL ENTPSSLNIE DIEDLFSLAQ YYCSKTPASF RKDNHHLFGS TLLGIKDDDA DLSQALCLAI SVSEILQANQ LQGEGVRFFV VDCRPAEQYN AGHLSTAFHL DSDLMLQNPS EFAQSVKSLL EAQKQSIESG SIAGGEHLCF MGSGREEEDM YMNMVLAHFL QKNKEYVSIA SGGFMALQQH LADINVDGPE NGYGHWIAST SGSRSSINSV DGESPNGSSD RGMKSLVNKM TVALKTKSVN VREKVISFIE NTSTPVDRMS FNLPWPDRSC TERHVSSSDR VGKPYRGVKP VFSIGDEEEY DTDEIDSSSM SDDDRKEVVN IQTWINKPDV KHHFPCKEVK ESGHMFPSHL LVTATHMYCL REIVSRKGLA YIQSRQALNS VVKITSKKKH PELITFKYGN SSASGIEILA IERYLIPNAG DATKAIKQQI MKVLDALES
-
分子量
78.3 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TBC1D23, a member of the TBC (Tre-2/Bub2/CEP-TBC) domain-containing protein family, has garnered significant interest in recent years due to its potential roles in cellular processes, particularly in vesicle trafficking and cellular signaling. Research suggests that TBC1D23 is involved in regulating the activity of Rab GTPases, which are crucial for the transport of cellular cargo and maintenance of cellular homeostasis. Mutations in TBC1D23 have been implicated in various diseases, including neurodegenerative disorders and cancer, highlighting its importance in health and disease. The protein has also been shown to participate in endosomal and lysosomal pathways, influencing autophagy and degradation processes. Therefore, understanding the functional mechanisms of TBC1D23, including its interactions with other proteins and its downstream effects, is vital for uncovering its biological significance and potential as a therapeutic target. The recombinant expression of TBC1D23 allows for the study of its structure-function relationships, enabling researchers to explore its role in cellular dynamics more comprehensively. Moreover, the study of TBC1D23 in the context of disease may uncover novel biomarkers and therapeutic strategies, reinforcing the value of this protein in biomedical research.
