Cat: PAX2000-11834

Recombinant Human TAS2R7 Protein,GST

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Analytical Data

  • Gene name

    TAS2R7

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    TAS2R7; Taste receptor type 2 member 7; T2R7; Taste receptor family B member 4; TRB4

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9NYW3

  • Expression Region

    1-318 aa

  • AA Sequence

    MADKVQTTLLFLAVGEFSVGILGNAFIGLVNCMDWVKKRKIASIDLILTSLAISRICLLCVILLDCFILVLYPDVYATGKEMRIIDFFWTLTNHLSIWFATCLSIYYFFKIGNFFHPLFLWMKWRIDRVISWILLGCVVLSVFISLPATENLNADFRFCVKAKRKTNLTWSCRVNKTQHASTKLFLNLATLLPFCVCLMSFFLLILSLRRHIRRMQLSATGCRDPSTEAHVRALKAVISFLLLFIAYYLSFLIATSSYFMPETELAVIFGESIALIYPSSHSFILILGNNKLRHASLKVIWKVMSILKGRKFQQHKQI

  • Molecular Weight

    62.9 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

TAS2R7, a member of the bitter taste receptor family, is a G protein-coupled receptor that plays a crucial role in the perception of bitter compounds, which can be important for dietary choices and the avoidance of potentially toxic substances. Research into TAS2R7 has gained interest due to its potential implications in various physiological processes, including taste perception, food preferences, and even metabolic regulation. Understanding the function and signaling pathways of TAS2R7 can provide insights into how bitter taste perception influences behavior and health outcomes. Furthermore, studies on TAS2R7 may have broader implications in fields such as pharmacology and toxicology, given that many environmental toxins and medications can elicit bitter taste responses. The production and characterization of recombinant TAS2R7 proteins have become a key focus of research, facilitating biochemical assays and advanced structural studies. Such work not only enhances our comprehension of the receptor's molecular mechanisms but also paves the way for potential therapeutic applications targeting taste-related disorders or enhancing the palatability of certain foods. Overall, ongoing research into TAS2R7 reaffirms the importance of taste perception in human health and disease, highlighting the intricate relationship between taste receptors and environmental interactions.

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