Analytical Data
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基因名
DSCR1L1
- Application
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别名
Calcipressin 2; Calcipressin-2; CSP2; Down syndrome candidate region 1-like 1; Down syndrome critical region gene 1 like 1 protein; DSCR1L1; MCIP2; Myocyte enriched calcineurin interacting protein 2; Myocyte-enriched calcineurin-interacting protein 2; RCAN2; RCAN2_HUMAN
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14206
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表达区间
1-225aa
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氨基酸序列
MPAPSMDCDVSTLVACVVDVEVFTNQEVKEKFEGLFRTYDDCVTFQLFKSFRRVRINFSNPKSAARARIELHETQFRGKKLKLYFAQVQTPETDGDKLHLAPPQPAKQFLISPPSSPPVGWQPINDATPVLNYDLLYAVAKLGPGEKYELHAGTESTPSVVVHVCDSDIEEEEDPKTSPKPKIIQTRRPGLPPSVSNWAACSFSIIAVSSLSCFFPLLFVKKNCL
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分子量
51.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The DSCR1L1 protein, a member of the Down Syndrome Critical Region 1 (DSCR1) gene family, has garnered significant attention in recent years due to its potential implications in various biological processes and diseases. Initially identified as a gene located within the critical region associated with Down syndrome, DSCR1L1 has been implicated in cellular stress responses, neuronal development, and immune regulation. Its expression has been found to be upregulated in certain pathological conditions, including neurodegenerative diseases and cardiac hypertrophy, suggesting a role in modulating cellular homeostasis and apoptosis. Additionally, research has highlighted DSCR1L1's potential as a biomarker for various diseases and its involvement in signaling pathways that influence cellular proliferation and differentiation. Given the growing interest in understanding the molecular mechanisms underlying its function, studies are now focusing on characterizing the protein's structure, its interactions with other cellular components, and its functional implications in health and disease. Insights gained from these investigations may contribute to the development of therapeutic strategies targeting DSCR1L1-related pathways, ultimately enhancing our understanding of complex conditions such as Down syndrome, cancer, and neurodegenerative disorders.
