Analytical Data
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基因名
FGF15
- Application
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别名
FGF15;C10orf112;DIET1;MAM and LDL-receptor class A domain-containing Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95750
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表达区间
23-216aa
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氨基酸序列
M+RPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK
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分子量
21.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Fibroblast growth factor 15 (FGF15), a member of the fibroblast growth factor family, plays a crucial role in various physiological processes, including metabolism, cell proliferation, and differentiation. It is predominantly expressed in the intestine and has been associated with the regulation of bile acid metabolism and energy homeostasis. Research has shown that FGF15 can act as a hormone-like signaling molecule, influencing hepatic lipid metabolism and glucose homeostasis. Emerging studies indicate that it may have therapeutic potential in metabolic disorders such as obesity and type 2 diabetes. The recombinant production of FGF15 protein is essential for detailed functional studies, allowing researchers to investigate its signaling pathways and biological effects in vitro and in vivo. The characterization of FGF15 through recombinant technology not only facilitates the exploration of its role in metabolic regulation but also paves the way for the development of novel therapeutic strategies targeting metabolic diseases. Understanding the mechanisms by which FGF15 exerts its biological effects could lead to innovative treatments that modulate its activity for beneficial outcomes in metabolic health. Thus, ongoing research into the recombinant expression and functional characterization of FGF15 protein is pivotal for advancing our knowledge of its roles in metabolism and potential clinical applications.












