Analytical Data
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Gene name
FGF15
- Application
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Alternative Names
FGF15；C10orf112；DIET1；MAM and LDL-receptor class A domain-containing Protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O95750
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Expression Region
23-216aa
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AA Sequence
M+RPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK
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Molecular Weight
21.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Fibroblast growth factor 15 (FGF15), a member of the fibroblast growth factor family, plays a crucial role in various physiological processes, including metabolism, cell proliferation, and differentiation. It is predominantly expressed in the intestine and has been associated with the regulation of bile acid metabolism and energy homeostasis. Research has shown that FGF15 can act as a hormone-like signaling molecule, influencing hepatic lipid metabolism and glucose homeostasis. Emerging studies indicate that it may have therapeutic potential in metabolic disorders such as obesity and type 2 diabetes. The recombinant production of FGF15 protein is essential for detailed functional studies, allowing researchers to investigate its signaling pathways and biological effects in vitro and in vivo. The characterization of FGF15 through recombinant technology not only facilitates the exploration of its role in metabolic regulation but also paves the way for the development of novel therapeutic strategies targeting metabolic diseases. Understanding the mechanisms by which FGF15 exerts its biological effects could lead to innovative treatments that modulate its activity for beneficial outcomes in metabolic health. Thus, ongoing research into the recombinant expression and functional characterization of FGF15 protein is pivotal for advancing our knowledge of its roles in metabolism and potential clinical applications.
