Analytical Data
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基因名
WDR69
- Application
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别名
DAW1; WDR69Dynein assembly factor with WDR repeat domains 1; Outer row dynein assembly Protein 16 homolog; WD repeat-containing Protein 69
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N136
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表达区间
1-415 aa
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氨基酸序列
MKLKSLLLRY YPPGIMLEYE KHGELKTKSI DLLDLGPSTD VSALVEEIQK AEPLLTASRT EQVKLLIQRL QEKLGQNSNH TFYLFKVLKA HILPLTNVAL NKSGSCFITG SYDRTCKLWD TASGEELNTL EGHRNVVYAI AFNNPYGDKI ATGSFDKTCK LWSVETGKCY HTFRGHTAEI VCLSFNPQST LVATGSMDTT AKLWDIQNGE EVYTLRGHSA EIISLSFNTS GDRIITGSFD HTVVVWDADT GRKVNILIGH CAEISSASFN WDCSLILTGS MDKTCKLWDA TNGKCVATLT GHDDEILDSC FDYTGKLIAT ASADGTARIF SAATRKCIAK LEGHEGEISK ISFNPQGNHL LTGSSDKTAR IWDAQTGQCL QVLEGHTDEI FSCAFNYKGN IVITGSKDNT CRIWR
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分子量
45.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WDR69, or WD repeat-containing protein 69, has gained attention in the field of molecular biology due to its potential role in various cellular processes, including cell cycle regulation, gene expression, and stress responses. As a member of the WD-repeat protein family, WDR69 is characterized by the presence of multiple WD40 repeats, which are known to facilitate protein-protein interactions and play crucial roles in the assembly of multi-protein complexes. Research has suggested that WDR69 may participate in key biological functions such as mitochondrial dynamics, cytoskeletal organization, and chromatin regulation, indicating its importance in maintaining cellular homeostasis. Furthermore, aberrations in the expression or function of WDR69 have been implicated in various diseases, including cancers and neurodegenerative disorders, highlighting its potential as a therapeutic target. The generation of recombinant WDR69 protein enables detailed biochemical and functional studies, providing insights into its mechanisms of action and potential roles in disease. Overall, WDR69 is a promising candidate for further exploration in the context of cell biology and disease research, warranting the development of advanced techniques for its expression, purification, and characterization in order to elucidate its biological significance.












